GRK Research Laboratories Private Limited is a Hyderabad, India based Contract Research Organization that provides chemistry services

GRK Research Labs team focuses on synthetic organic chemistry to speed up agrochemical discovery of field candidates and drug discovery research programs in identifying pre-clinical candidates. Our capabilities Crop Science Discovery Chemistry: GRK Research Labs can support for new agrochemical discovery programs in developing crop protection chemicals. Hit Identification: Synthesis of singletons and synthesis of small focused arrays Hit to lead: Structural modification of hits to improve potency and selectivity Lead Optimisation: Development of selected candidates Drug Discovery Medicinal Chemistry: GRK Research Labs can support to speed up drug discovery research programs in identifying pre-clinical candidates. Hit to Lead: Small to big libraries are designed and synthesised using parallel chemistry techniques in 1 – 50mg scale with chemical purities of ≥95% (by LC-MS and NMR) for clients generated Hits through High Throughput Screening (HTS). Lead Optimization: To rapidly confirm Structure Activity Relationship (SAR) and to improve potency and selectivity, we design novel molecules and synthesise using parallel chemistry techniques. Focused arrays of 20 – 50 compounds in 1 – 50mg scale with chemical purities of ≥95% (by LC-MS and NMR) can be synthesised for rapid in vitro screening and in vitro ADMET profiling. Selected candidates can be quickly scaled up for pre-clinical studies.

GRK Research Laboratories Private Limited is a Hyderabad, India based Contract Research Organization that provides chemistry services

GRK Research Labs team focuses on synthetic organic chemistry to speed up agrochemical discovery of field candidates and drug discovery research programs in identifying pre-clinical candidates. Our capabilities Crop Science Discovery Chemistry: GRK Research Labs can support for new agrochemical discovery programs in developing crop protection chemicals. Hit Identification: Synthesis of singletons and synthesis of small focused arrays Hit to lead: Structural modification of hits to improve potency and selectivity Lead Optimisation: Development of selected candidates Drug Discovery Medicinal Chemistry: GRK Research Labs can support to speed up drug discovery research programs in identifying pre-clinical candidates. Hit to Lead: Small to big libraries are designed and synthesised using parallel chemistry techniques in 1 – 50mg scale with chemical purities of ≥95% (by LC-MS and NMR) for clients generated Hits through High Throughput Screening (HTS). Lead Optimization: To rapidly confirm Structure Activity Relationship (SAR) and to improve potency and selectivity, we design novel molecules and synthesise using parallel chemistry techniques. Focused arrays of 20 – 50 compounds in 1 – 50mg scale with chemical purities of ≥95% (by LC-MS and NMR) can be synthesised for rapid in vitro screening and in vitro ADMET profiling. Selected candidates can be quickly scaled up for pre-clinical studies.