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Amoxicillin Side Effects Common side effects of amoxicillin include: Upset stomach Diarrhea Vomiting Yeast infection Serious side effects of amoxicillin can also occur. If you have any of these side effects, stop taking amoxicillin and call your doctor right away: Severe rash Yellowing of the skin or eyes (jaundice) Unusual bleeding or bruising Hives Seizure Excessive tiredness Swelling of the face, lips, or tongue Chest pain Difficulty breathing A peeling or blistering rash Severe or bloody diarrhea