Clostebol Acetate (Turinabol)

Clostebol acetate is a mild anabolic steroid with low androgenic effects and moderate anabolic effects. It is mainly produced for cattle, but its use has been banned by many countries, although this is not due to their health problems in the treatment of animals (1,2). The results produced in the treatment of animals as well as some studies have shown that the drug is suitable for certain treatments of humans (3) and is of interest to the athlete and bodybuilder of the compound.

Due to its low androgen and synthetic metabolic properties, most of the phenylephrine acetate is considered to be mild synthetic metabolites. It does not show the chemical composition that produces many other drug strengths and / or increased muscle mass. However, the user does not produce serious androgen or estrogen side effects. The lack of estrogen side effects is due to the insufficient ability of the compounds to aromatize the compounds due to the 4-chloro substitution in the A ring of the compound (4). This change itself eliminates the possibility that most male users have estrogen side effects.

Clostebol acetate appears in several versions. Injections, oral or even topical creams have been made. However, only oral and injectable drug versions are suitable for use by powerful athletes and bodybuilders. The current production of local creams and ointments is not effective in trying to get muscle and strength.

The use of 4-chlorotestosterone acetate by farmers for cattle fattening was recently demonstrated although the use of this anabolic steroid is strictly forbidden in the European Union. We investigated the metabolism of 4-chlorotestosterone acetate in the bovine species after intramuscular and oral administration. Nineteen metabolites were detected in urine after intramuscular injection, and eight metabolites were identified. For this purpose, preparative HPLC, mass spectrometry with different ionization modes (electronic impact and chemical ionization), and different acquisition techniques were used (high resolution, selected ion monitoring, and scan measurement). Metabolite stereoisomerism was determined on the basis of retention time and organic synthesis.