Cyproheptadine Hydrochloride

CYPROHEPTADINE HYDROCHLORIDE IS A SEROTONIN ANTAGONIST AND A HISTAMINE H1 BLOCKER USED AS ANTIPRURITIC, APPETITE STIMULANT, ANTIALLERGIC, AND FOR THE POST-GASTRECTOMY DUMPING SYNDROME, ETC.
CYPROHEPTADINE HYDROCHLORIDE IS THE HYDROCHLORIDE SALT OF A SYNTHETIC METHYL-PIPERIDINE DERIVATIVE WITH ANTIHISTAMINIC AND ANTI-SEROTONINERGIC PROPERTIES. CYPROHEPTADINE COMPETES WITH FREE HISTAMINE (HA) FOR BINDING AT HA-RECEPTOR SITES, THEREBY COMPETITIVELY ANTAGONIZING HISTAMINE STIMULATION OF HA-RECEPTORS IN THE GASTROINTESTINAL TRACT, LARGE BLOOD VESSELS, AND BRONCHIAL SMOOTH MUSCLE. THIS AGENT ALSO COMPETES WITH FREE SEROTONIN FOR BINDING AT SEROTONIN RECEPTOR SITES. CYPRO HEPTA DINE EXHIBITS ANTICHOLINERGIC AND SEDATIVE PROPERTIES AND HAS BEEN SHOWN TO STIMULATE APPETITE AND WEIGHT GAIN.