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Nervigesic 450 mg capsule is a medicine used to relieve pain caused by nerve damage (neuropathic pain) due to diabetes, shingles (herpes zoster infection), spinal cord injury, or other conditions. It is also used to treat widespread muscle pain and stiffness in people with fibromyalgia.

Mode of action

When given for epilepsy, it is believed to work by reducing the abnormal electrical activity in the brain, thus preventing seizures. It is also used to treat nerve and muscle pain where it blocks pain by interfering with pain signals traveling through the damaged nerves and the brain.

Dosage

As directed by the physician

Side effects

The most common side effects are feeling sleepy or dizzy, dryness in the mouth, blurred vision, weight gain, edema

Nervigesic Capsule contains Pregabalin, which is an anticonvulsant and anti-neuropathic pain agent. It is primarily used to treat nerve-related pain (neuropathic pain), seizures, and certain anxiety disorders. Pregabalin works by affecting the way that nerves send signals to the brain, helping reduce pain and seizures.

• Active Ingredient: Pregabalin
• Drug Class: Anticonvulsant and Neuropathic Pain Agent

• Neuropathic Pain: Commonly prescribed for conditions like diabetic neuropathy, post-herpetic neuralgia (pain following shingles), or nerve damage caused by spinal cord injuries.
• Fibromyalgia: Can help reduce the pain associated with fibromyalgia, a condition characterized by widespread musculoskeletal pain.
• Seizures: Used as an adjunctive therapy for partial-onset seizures.
• Generalized Anxiety Disorder (GAD): May be prescribed for the treatment of generalized anxiety disorder in some cases.

• Pregabalin works by binding to specific calcium channels in the central nervous system, reducing the release of certain neurotransmitters like glutamate, norepinephrine, and substance P. This action helps reduce the overactivity of nerve cells, which in turn reduces pain and the occurrence of seizures.

• The dosage depends on the condition being treated and is usually determined by the healthcare provider.
  • For neuropathic pain: Typically, the starting dose is 75 mg twice daily, and it may be increased as needed based on the patient's response and tolerability.
  • For epilepsy: The dosage is usually adjusted based on the frequency of seizures.

• Dizziness and Drowsiness: Pregabalin can cause dizziness and drowsiness, so activities requiring alertness, such as driving or operating machinery, should be avoided until you know how the medication affects you.
• Kidney Function: Pregabalin is primarily excreted by the kidneys, so individuals with kidney problems may need dose adjustments.
• Avoid Alcohol: The sedative effects of Pregabalin can be enhanced by alcohol, leading to increased dizziness and drowsiness.
• Dependence and Withdrawal: Although less common, Pregabalin has some potential for dependence, particularly with prolonged use. Abrupt discontinuation should be avoided to prevent withdrawal symptoms.

• Common side effects:
  • Dizziness
  • Drowsiness
  • Dry mouth
  • Blurred vision
  • Weight gain
• Serious side effects:
  • Mood changes (depression, anxiety)
  • Swelling in hands or feet
  • Difficulty breathing (rare)

Nervigesic Capsules, containing Pregabalin, are mainly prescribed to treat nerve-related pain, seizures, and anxiety disorders. They work by calming overactive nerves, reducing pain, and preventing seizures. Caution is needed when using this medication due to its potential for causing drowsiness and dizziness.