S.B. Panchal & Company

Dadar, Mumbai, Maharashtra

Wurster Coaters applies to a smaller range of pellets. This type of coating method is frequently used for applications in which a large amount of coating or drug layer is applied to a substrate. A special designed partition is made for coating very fine, cohesive powder. Wurster fluid bed coating processcan provide a film coat of the highest quality and uniformity compared to other techniques. This uniformity can minimize coating thickness requirements, further reducing the amount of coating materials needed and the processing time. The Wurster coating process can be applied to a range of core materials in numerous particle sizes and shapes. The process is flexible enough to coat small particles for use in capsules and tablets, as well as coating the full capsules and tablets. Coating capabilities extend all the way to coating soft gels capsules, extruded materials, powders, crystals and granules. No matter the shapespherical, crystalline, irregular, amorphousthe Wurster process is capable of creating a unique formulation to achieve the desired properties.

A high shear granulator also called as RAPID MIXER GRANULATOR comprises of a three-bladed impeller and an auxiliary chopper. The impeller is employed to mix the dry powder & spread the binder or granulating fluid. The function of the chopper is to break down the wet mass to produce granules. A high shear wet granulation process advantages are mentioned below: Short processing timeGranulation of highly cohesive materials containing hydrophilic polymers which is not achievable using low shear granulation processesGreater densification & production of less friable granules.Narrow size distribution.Reduction of process dust.

Fluidization is a process by which fine solids are transformed into a fluid like state through contact with a gas. The properties (density, viscosity) bed of solids tend to be similar to those of a liquid hence the name; FLUID BED.The heat & mass transfer co-efficient of a fluid bed are very high as compared to conventional state beds. These physical phenomenon is exploited to design UNIFLUID series of fluid bed processing systems by S.B. Panchal & Company.Fluidized bed Granulation is a process by which granules are produced by spraying a fluid bed are very high as compared to conventional state beds. These physical phenomenon is exploited to design UNIFLUID series of fluid bed processing systems by S.B. Panchal & Co.

Rotating screws are used to convey the product from feed hopper to pressing flutes or rollers. Pressing flutes extrude the mass through holes present on die plates. Screw extruders are available in radial, conical and axial die configurations.

A combination of roller and knurling roller produce cylindrical extrudates. In this extruders the length of the cylindrical extrudates can be controlled by cutting blade present on inner surface of roller.

Basket Extruders: Basket extruders are vertical extruders. Vertically rotating rollers press the formulated mass through perforated mesh. This process gives lighter granules.

Hot Melt Extruder -These extruders are a modification of screw extruders. A carefully controlled heater heat the barrel which conducts the heat to the product. The molten polymeric mass is extruded from the die plates.

UNILAYER is a single pot processing system for solid drug layering. Process involves deposition of successive layers of an active drug layered pellets. Reduction in manufacturing times and costs are achieved due to more efficient application of liquids and powder.

Fluidized bed drying is the optimal method for controlled, gentle and even drying of wet solids. The intensive heat/mass exchange of the fluidized bed product makes this method particularly effective and time-saving. The technology is also suitable for post-drying of spray granulated or extruded products with very low residual moisture. Fluidized bed drying can be used in the entire powder processing industry. In the pharmaceutical industry, this innovative method has replaced the time-consuming tray drying long ago. In addition, fluidized bed drying provides controlled and uniform drying conditions compared to the uneven drying in trays. Properly used, fluidized bed drying provides an efficient solution for the gentle and even drying of your product.

S.B. Panchal & Cos UNIVAC series of vacuum drying system consists of drying oven with a heating system, vapor condensing system, and a vacuum pump assembly designed specifically for drying a particular product and to achieve the desired objective for which product is dried under vacuum. Vacuum Drying is ideally suited for pharmaceutical industry where products cannot be exposed to very high temperatures. These may include biotechnology products or pharmaceutical intermediates. Extremely low moisture/solvent content can be achieved to meet residual solvent limits set by ICH. Expensive solvents can be recovered and recycled in the process. Potentially toxic materials can be safely dried in an enclosed vacuum environment and solvent can be safely condensed.

Spray Drying is a unique method to convert a solution, suspension or emulsion into a solid powder in one single process step. It is a widely established process in many industries such as pharmaceuticals, food, chemical or material science. Spray Drying consists of three basic steps, drying begins with atomization of a liquid feed into a spray of fine droplets. The spray is then contacted with, and suspended by, a heated gas stream, allowing the liquid to evaporate and leave the dried solids in essentially the same size and shape as the atomized droplet. Finally, the dried powder is separated from the gas stream and collected. The spent drying gas is treated to meet environmental requirements and then exhausted to the atmosphere or, in some cases, recirculated to the system.

S.B. Panchal & Cos Unisafe series of tray drying system are designed specifically keeping in mind the safety considerations required when drying solvents based pharmaceutical powders/granules or tablets which if not taken in consideration can lead to explosion. Though safety is a prime design consideration the system is very simple and complies easily with GMP norms critical for pharmaceutical manufacturing units. Unique air distribution system comprising of distribution baffles ensures that the drying quality is uniform throughout the height of the trolley. Flexible and modular air handling unit ensures that the installation of the machine is possible even in most trying site conditions.

Octagonal Blender, the unique octagonal shape is designed to process larger volume of material for efficient angular momentum of the powder to achieve blend uniformity. It is ideal for gentle blending of dry granules or for powder mixing and has wide applications range across many industries. cGMP construction with cladded polished S. S. Sheets with S.S 316 Contact parts and 304 Non-Contact partsLower Power consumption than other tumble blendersSlow speed Blender with Gentle blending of Dry granules and powderZero Jerk Load as machine is both dynamic and statically balancedPneumatically actuated valves for dust free transfersBins with Level sensory for automatic cut offMechanical Seals on shafts for Pneumatic connectionscGMP design for ease of cleaning

Double Cone Blender is an efficient and versatile equipment for mixing of powder such as pharmaceutical excipients, various chemicals, food products homogeneously. With an effective volume for optimum homogeneity between 35-70% of gross volume. cGMP construction with cladded polished S. S. Sheets with S.S 316 Contact parts and 304 Non-Contact partsConical shape and elongated plane at both ends enables uniform mixing and easy dischargeThe cone is statically balanced which protects the gear box and motor from any excessive loadPowder is loaded into the cone through a wide opening and discharged through a butterfly or a Slide valvePaddle type baffles can be provided on the shaft for better mixing, uniform blending and de-agglomeration

cGMP construction with cladded polished S. S. Sheets with S.S 316 Contact parts and 304 Non-Contact partsDesigned for dust free blending and transfer of powders and granulesHome position docking and undocking of the binGuard around the cage with an entry point for the bin on detachable trolleyLimit switch on entry door to prevent accidental operation of the cagecGMP construction with cladded polished S. S. SheetsContainers of Varying size for varying batch sizeBuilt-in Butterfly valve (150 mm dia) at the bottom for dischargeSuitable leak proof vent on top

Ribbon Blender is a light duty, compact blender designed to achieve convection mechanism of blending powder components which are pre-processed like dried granules, pre-sieved powders etc. It is a LOW SHEAR mixer and ideal for SOLID / SOLID Mixing. Solid / Liquid mixing can also be achieved when high shearing force is not desired. All contact parts in SS 316LBatch size based on 65% of Blender volumeDesigned to avoid Cross contamination with Mono block DesignBearing mounted on lanterns out of mixing zoneAir purge on the side entry sealsMeets all cGMP/cGEP standardsContinuous Ribbon design for complete dischargeVariable frequency drive for fine tuning the Shear energyBelt driven power transmission

All contact parts of the mixing bowl and beater are made out of S.S 316. Scrapping bladers can also be provided if required.The mixing bowl can be jacketed for electric/ steam/thermic fluid heating.Ideal equipment for small batch sizes.Manual lifting arrangement for agitator up to 50 lits and motorized lifting arrangements for capacities of 100 litters and above can be provided.The top of the mixing bowl has an S.S. lid with a charging hole.The mixing bowl is provided with castor wheels and locking system for easy handling and transportation.VSHSE option can be provided.

All contact parts are made from S.S 316.High output with process uniformityMachine is rated for continuous operation.Various combinations of Screen/speeds/ numbers of blades/ direction of rotation of blades, can be selected.Higher screen opening area for higher through put.Alll components can easily be dismantled and cleaned for change of product.Wide range of S.S perforated and wire knitted screen availableDust free operation.

Cone mill works on the principle of Centrifugal Shearing force. In agglomerating materials of wet granulation, it is used for high speed shredding, sizing and grinding of powder granules. Cone mill screens is ideal for handling viscous clumps, gums and wet material.

GMP model with Control Parts in S.S. 316 and Non-contact parts in S.S. 304.Amplitude of vibratory motion adjustable through moveable eccentric weight.S.S. 316 Hood with 200 mm dia Nozzle for dust free charging of powders.The machine can easily be dismantled, cleaned and assembled through quick opening S.S. 316 clamps.Portable, mounted on sturdy Castor wheels. The vibrating assembly is isolated by rugged springs.FinishInside- 0.3 Ra. mirror polishOutside- 0.3 Ra. Mirror Polish

Product Bins represent a standard solution for handling and storing pharmaceutical tablets. They are designed and manufactured for handling through their own trolley, offering the advantage of trolley release at floor when the container is lifted to be placed on process machines like tablet presses, sachet filling machines etc. Rounded edges and corners to avoid product retention points.Completely smooth surfaces suitable for pharmaceutical products.Working capacity for good mixing min. 30% - max. 70%.AISI 316 stainless steel.Discharge butterfly valve with manual opening/closing.