We are offering milk thistle plus medicine. Silybum marianum (thistle) , silymarine is a compound that contains silybin, silychristin and silydianin as main components. Silymarine is used on treatment of cirrhosis t. It protects liver and provides therapeutic efficacy by inhibiting access of toxins to liver and toxins connected out of cell membrane of liver. Liver’s potential to renew itself increases by increasing ribosomal protein synthesis due to silymarine. Liver cells’function decreases by drugs, smoking, alcohol. Artichoke leaf is used for renewal of liver cells and treatment of liver failure. Artichoke preparations are used very extensively for problems of bloating and indigestion. Artichoke leaf extract increases bile production of liver and decreases amounts of cholesterol, ldl and triglyceride so that it provides a properfunctioning of gall bladder and helps digestion. Dandelion root helps digestion with its diuretic effect while making detox. Grape seed extract has a wide range of pharmacological activity with its antioxidant, anti-inflammatory, antimicrobial, cardio protective, hepatoprotective, neuroprotective effects. Besides cardiovascular protective and chemopreventive effects of the other phytochemicalswith proantocianidins found in grape seed. Clinical researches have proven that grape has effective compositions on alzheimer disease, decreases thrombocyt aggregation.recovers endothelial functions and balances blood pressure