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Tamoxifen

Listing ID #3271950

  • MOQ 25 Kilogram
  • WHITE CRYSTALLINE SOLID POWDERWHITE CRYSTALLINE SOLID POWDER
  • Supply Type Manufacturer, Exporter, Supplier
Preferred Buyer From : All over the world

Tamoxifen is an estrogen agonistantagonist. The mechanism of action of tamoxifen is as a selective estrogen receptor modulator one of the selective estrogen receptor modulators with tissue-specific....
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  • Member Since 9 Years
  • Nature of Business Retailer
  • GST No. 27AGPPS8689E1ZF

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Tamoxifen is an estrogen agonistantagonist. The mechanism of action of tamoxifen is as a selective estrogen receptor modulator one of the selective estrogen receptor modulators with tissue-specific activities. Tamoxifen acts as an anti-estrogen (inhibiting agent) in the mammary tissue but as an estrogen (stimulating agent) in cholesterol metabolism, bone density &cell proliferation in the endometrium.tamoxifen base is an antineoplastic nonsteroidal selective estrogen receptor modulator (serm). Tamoxifen competitively inhibits the binding of estradiol to estro- gen receptors, thereby preventing the receptor from binding to the estrogen-response element on dna. The result is a reduction in dna synthesis & cellular response to estrogen. In additiontamoxifen up-regulates the production of transforming growth factor b (tgfb), a factor that inhibits tumor cell growth & down-regulates insulin-like growth factor 1 a factor that stimulates breast cancer cell growth.


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