ALL Chemistry Inc.

Ethyl 3-(furan-2-yl)propanoate is a reactive compound that can be used as a photooxidation sensitizer in organic synthesis. The compound is highly reactive, and has been shown to undergo oxacycles with acetonitrile.

cis-3-Nonen-1-ol is a chemical compound that is found in the gland cells of plants. The compound has been found to have insecticidal properties and can be used as an active ingredient in pesticides.

O-Demethylmurrayanine and clausine D exhibit strong cytotoxicity against MCF-7 and SMMC-7721 with IC50 values in the range 2.63-7.59 ug/ml.

Senecionine N-oxide and senecionine have hepatotoxic activity, no antifertility effects in MeOH extract-treated hamsters.

Sinapine is a natural product that is found in the leaves and bark of plants. Sinapine has shown to have insecticidal properties, which may be due to its ability to inhibit the polymerase chain reaction (PCR) and transfer reactions.

N-(3-Methoxybenzyl)Oleamide has pharmaceutical property against exercise-induced fatigue, and this effect can be explained by the modulated energy metabolism and improved antioxidant status.

Adenine, a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemical component of DNA and RNA.

Melatonin is a biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.

1. Chelerythrine may have antimanic effect . 2. Chelerythrine can inhibit telomerase activity. 3. Chelerythrine is a well-known protein kinase C inhibitor . 4. Chelerythrine has potential antiproliferative and antitumor effects.

Niacinamide is an important compound functioning as a component of the coenzyme NAD.

Pingpeimine A has the effect of expectorating and lowering blood pressure. Derived from Fritillaria sibiricum.

Guanine is a purine base that is a constituent of nucleotides occurring in nucleic acids.

Falnidamol (BIBX 1382) is an orally active, selective EGFR tyrosine kinase inhibitor with an IC50 of 3 nM. Falnidamol is 1000 times more selective for ErbB2 (IC50=3.4 μM) and a range of other related tyrosine kinases (IC50 >>10 μM). Falnidamol is a pyrimidine-pyrimidine compound with anti-cancer activity.

Cerdulatinib is an novel oral dual Syk/JAK inhibitor.

JAK2 inhibitor G5-7 is an orally active JAK2 inhibitor, selectively inhibits JAK2–mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 has the potential for glioma study.

Concanavalin A is a plant lectin that is a T cell mitogen. It induces apoptosis in human fibroblasts.

Tetramethylcurcumin is a novel curcumin analog, is an effective inhibitors of STAT3 phosphorylation, DNA binding activity, and transactivation in vitro.it also inhibits colony formation in soft agar, cell invasion, and exhibit synergy with the anti-cancer drug doxorubicin against breast cancer cells.

Bisindolylmaleimide VIII acetate is a potent and selective PKC inhibitor (IC50: 158 nM for rat brain PKC). It has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively.

Gossypol-acetic acid, a polyphenolic compound isolated from cottonseeds, binds with Bcl-2, Bcl-xL, Mcl-1, and does not inhibit BIR3 domain and BID.

Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.

• Packaging Size1-5 Ltrs
• Purity99%
• FormLiquid
• Brand NameALL Chemistry Inc.
• ApplicationHousehold Products
• Number Of FlowerFlavors Fragrances

FN-1501 is a potent FLT3 and CDK inhibitor (IC50s: 2.47, 0.85, 1.96, and 0.28 nM for CDK2/cyclin A, CDK4/cyclin D1, CDK6/cyclin D1 and FLT3, respectively). FN-1501 also has anticancer activity.

CP 31398 dihydrochloride is a p53 stabilizer which stabilizes the active conformation of p53 and promotes p53 activity in cancer cell lines with mutant or wild-type p53.

RIPK1-IN-7 is a potent and selective inhibitor of RIPK1(Kd of 4 nM and an enzymatic IC50 of 11 nM), andexhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model.

SP-8356 is a potent, orally active inhibitor of cluster of differentiation 147 (CD147) with anti-atherosclerotic effects.

Pyridone 6 is a potent and selective inhibitor of JAK1 (IC50=15 nM, murine JAK1), JAK2 (IC50=1 nM), JAK3 (Ki=5 nM), and Tyk2 (IC50=1 nM); displaying significantly weaker affinities (130 nM to 10 mM) for other protein tyrosine kinases.

Indisulam is a carbonic anhydrase inibitor and Antitumor CDK inhibitor. Indisulam targets the G1 phase of the cell cycle by depleting cyclin E. inducing p53 and p21, and inhibiting CDK2, causing a blockade in the G1/S transition.

Thapsigargin is a microsomal Ca2+-ATPase inhibitor and Endoplasmic Reticulum stress-inducing agent.

Decanoic acid is used in manufacturing of esters for artificial fruit flavors and perfumes.

(-)-Cephaeline (dihydrochloride) is an enantiomer of Cephaeline. Cephaeline is a selective CYP2D6 inhibitor.

• BrandALL Chemistry Inc.

Cetrimonium Bromide (CAS 57-09-0) is is a mixture of different quaternary ammonium salts, which is a known component of the broad-spectrum antiseptic cetrimide.

1-Naphthyl PP1 hydrochloride is a selective inhibitor of src family kinases v-Src.

Oglufanide is a naturally occurring thymic immunomodulator, and inhibits vascular endothelial growth factor (VEGF).

• BrandALL Chemistry Inc.

ALL Chemistry Inc. can quickly conduct thousands of experiments to identify ‘hits’ for appropriate biological responses through the use of automated robotics, liquid handling, imaging, and data analysis systems. By using modern screening technology,   ALL Chemistry Inc. assists our global customers in drug research and development, thereby accelerating the process of drug innovation.  ALL Chemistry's compound screening platform provides both phenotypic and target-based methodologies. Our capacity reaches approximately 100, 000 sample screenings per day. Customers only need to hand over the compound library to us, and we will screen potential compounds through standard experimental procedures. Our Advantages *Diverse and complete compound libraries *Customizable services *Advanced equipment *Excellent professional, efficient and well-established team *Deliver tasks on time  

• Brand NameALL Chemistry Inc.

25000+ chemical compounds; Free guidelines for small molecule inhibitor selection; Covering all kinds of hot singling pathways;  High specificity and selectivity;  Low toxicity and high potency;  Or in libraries format for HTS.  

Verteporfin, a benzoporphyrin derivative monoacid ring A, can inhibit the activity of YAP.

Pomalidomide inhibits TNF-α release in LPS stimulated human PBMCs (IC50: 13 nM). It is an anti-angiogenic agent and an immunomodulator.

• Cultivation TypeNatural

Adenosine is a ribonucleoside comprised of adenine bound to ribose, with vasodilatory, antiarrhythmic and analgesic activities.

• BrandALL Chemistry Inc.

ALL Chemistry Inc. has collected more than 40000 bioactive compounds with known bioactivity, covering all areas of biomedical research and development, including enzyme inhibitors, receptor ligands, and ion channel regulators for different molecular targets (such as kinases, GPCRs, ion channels) and activity areas (e.g. biotechnology, epigenetics, antiviral or antibacterial research). Meanwhile, ALL Chemistry Inc. offers customized bioactive compound library service at various stages, from compound library creation, storage, to management. For customized bioactive compound library you can choose: *Specific compounds *Quantities *Plate Map (96/384-well) *Concentration (5 - 50 mM) *Format (Pre-dissolved DMSO Solution or Solid)

• BrandALL Chemistry Inc.

ALL Chemistry Inc. is a Contract Research Organization (CRO) that enables you to outsource a broad variety of research activities from custom synthesis of small molecules to clinical trials of a new drug, which helps you to enliven the commercial research culture toward an international, innovation-based (drug) industry. Our Services: * Route scouting * Laboratory trial * Pilot production * Process optimization * Multistep organic synthesis * Custom packaging * Synthesis report in the agreed format Advantages: • Respond to inquiries within 24 hours • Typically 3-4 weeks turnaround time • Strict quality control (QC by HPLC, NMR, GC/LC/MS) • High quality compound synthesis from mg to kg • Independent synthetic route design • Following the principles of green chemistry   • Intellectual property and data integrity protection