World Precision Instruments, Inc.

United States

• Plug up to 3 probes into a single unitLCD readout
• LCD readoutOptional analog output cable for chart recorder

Complete stagetop environment (STEV) and ECU-HCP Environmental Control Unit Monitor and control the CO2 and O2 flow and temperature in a microcope chamber or stagetop environment Includes external temperature probe

tem#: II-2500 Hands free operation with footswitch Visible force limit indicator Portable electronic display Battery-operated or line powered controller THIS SITE REQUIRES JAVASCRIPT AND THIRD PARTY COOKIES TO PLACE AN ORDER. For pricing, Customers outside of the US and Canada, pleaThe Randall Selitto Paw Pressure Meter for analgesia testing is digitally controlled. Use the handheld instrument to apply force to an animal’s extremity and get instantaneous, live readings. You can even view the last maximum force applied during the test. The new limit indicator lets you select the maximum force limit, and then indicates with a warning light when the system reaches that limit. This unit comes with an acrylic stand to allow for easy viewing of the display. Stand and sling are sold separately. This unit features: Hands free operation with footswitch Visible force limit indicator Portable electronic display Battery-operated or line powered controller 3-oz. handheld probe with accuracy of 0.5% No calibration required 800g pressure applicator included

For use with EZ Anesthesia Systems Up to five mice or three rats All ports operate in a level plane of anesthesia Single gas line supplies multiple outputs Exhaust runts to a charcoal filter for safety

Measure muscle hyperalgesia in rats and mice with the Grip Strength Meter, which gauges the forelimb grip force using a digital force transducer. Simply hold the animal by the tail and gently dangle it over the wire mesh plate until the animal grasps the plate with its forepaws. The force transducer, connected with the wire mesh plate, measures the strength of the animal at the time of the test. The battery-operated, electronic control device calculates the average of three measurements, and it holds the last maximum force in a “peak and hold” type readout until you reset it. This unit features: Mouse and rat wire mesh grid plates included Maximum force range is 2, 000 gm (10% over range allowed). Higher ranges are available by special order. 1 gram increment readings Suction feet on the heavy, anodized base plate resist even large pulling forces Battery-operated or line powered controller One year warranty

An emerging area of research (Live Cell Imaging) is growing rapidly. The number of PubMed articles published on live cell imaging has bloomed in the last several years, and is 10 times greater this year than in 2003. WPI, working in tandem with researchers from InVivo Scientific, has develop a cutting-edge line of products specifically for live cell imaging. In the past dead cells were stained and examined under a microscope. Now, small incubators can be placed on a microscope stagetop and live cells in culture can be observed directly. This opens a whole new world for exploration.

Cuvettes and HoldersFor spectroscopy cuvettes, synthetic quartz can be used in deep UV applications and is recommended for fluorescent applications, as it does not exhibit background fluorescence. Our quartz cuvettes are shipped individually packaged. Our glass cuvettes are shipped in packages of 10 cuvettes. These economical quartz and glass cuvettes are ideal for precision measurements, because of the high quality materials used and the low manufacturing tolerances. Cuvettes come in a variety of shapes and sizes, but one of the most important specifications of a cuvette is its Z-dimension. The Z-dimension of an instrument (cuvette holder or spectrometer) is the distance from the bottom of the cuvette chamber floor to the center of its light beam (see image). A cuvette’s Z-dimension must match the Z-dimension of the instrument with which it will be used. Compare manufacturers' Z-dimensions and learn how to measure a Z-dimension.

Analgesia testing is a growing field. Before new pain killing pharmaceuticals are brought to market, they must undergo a host of efficacy studies involving some form of analgesiometry prior to any clinical trials. The standard nociceptive threshold testing for preclinical trials involve mechanical, thermal and chemical stimuli with mice and rats. WPI offers a variety of such equipment.

EZ Anesthesia is the system of choice for anesthetizing small animals, and it comes with a variety of choices. Animals to be anesthetized are placed in the acrylic induction chamber and the system delivers a precisely blended mixture of oxygen and isoflurane. An activated charcoal air filter canister at the top of the chamber releases safe, filtered air back into the room. A water-heated cage warmer or warming plate (ATC2000) is used to retain the animal body temperature while in the induction chamber. After the initial anesthetizing, the animal can be moved to the heated surgical water bed and positioned properly in the snugly fitted nosecone. A highly sensitive valve regulated by the animal’s breathing works with the nosecone to ensure non-rebreathing efficiency, .