Bortezomib for injection is an antineoplastic agent available for Intravenous Injection (IV) use only. Each single use vials contains 2 mg of bortezomib as a sterile lyophilized powder. Bortezomib id modified dipeptidylboronic acid. The Product is provided as a mannitol boronic ester which, in reconstituted from, consist of the mannitol ester in equilibrium with its chydrolysis product, the Monomeric boronic acid. The substance exits in its cyclic anhydride from as a trimericboroxine. The chemical name for bortezomib, the monomeric boronic acid, is [(1R)-3-methyl-1[(2S)-1-oxo-3-phenyl-222-(pyrazinycarbony) amino]propyl]butyl] boronic acid.

Zuvitop-100 (etoposide Injection, IP) is a semisynthetic derivative of podophyllotoxin used in the treatment of certain neoplastic diseases. It is 4'-demethylepipodophyllotoxin 9-[4, 6-0-(R)- ethylidence - B-D- glucopyranoside]. It is very soluble in methanol and chloroform, slightly soluble in ethanol, and sparingly soluble in water and ether. It is made more miscible with water by means of organic solvents. It has a molecular weight of 588.58 and a molecular formula of C29 H32 O13.

Etoposide, the active ingredient of zuvitop-50 is a semisynthetic derivative of podophyllotoxin used in the treatment of certain neoplastic diseases, . It is available as capsules of 50mg and 100mg.

Tamoxifen, a nonsteroidal antiestrogen, is a triphenylethylene derivative with both estrogen antagonist on breast tissue and in the CNS and as an estrogen agonist on endometrium, bone and lipids. Tamoxifen and at least several of its metabolites compete with estradiol for binding to cytyplasmic estrogen receptors in tissues such as breast, uterus, vagina, anterior pituitary, and tumors containing high concentrations of estrogen receptors.

Fluorouracil injection, an antineoplastic antimetabolite, is a sterile, nonpyrogenic injectable solution for intravenous administration. Each ml contains 50 mg fluorouracil in water for injection, ph is adjusted to approximately 9.2 with sodium hydroxide. Chemically, fluorouracil, a fluorinated pyrimidine, is 5-fluoro-2, 4 (1h, 3h)-pyrimidinedione. It is a white to practically white crystalline powder which is sparingly soluble in water. The molecular weight of fluorouracil is 130.08

Pemetrexed disodium heptahydrate has the chemical name L-Glutamine acid, N-[4-[2-(2-amino-4, 7-dihydro-4-oxo1H-pyrrolo[2, 3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. It is a white to almost-white solid with a molecular formula of C20H19N5Na2O67H2O and a molecular weight of 597.49.

Epirbicin is an anthracycline cytotoxic agent and forma a complex with DNA by interacalation of its planar rings between nucleotide base pairs, with consequent inhibition of nucleic acid (DNA & RNA) and protein synthesis, Such intercalation triggers DNA cleavage by topoisomerase II, resulting in cytocidal activity, Epirubicin also inhibits DNA helicase activity, preventing the enxymatic seperation of double - standard DNA & interfering with replication and transcription. Epirubicin is also involved in oxidationreduction reactions by generating cytotoxic free radicaEpirbicin is an anthracycline cytotoxic agent and forma a complex with DNA by interacalation of its planar rings between nucleotide base pairs, with consequent inhibition of nucleic acid (DNA & RNA) and protein synthesis, Such intercalation triggers DNA cleavage by topoisomerase II, resulting in cytocidal activity, Epirubicin also inhibits DNA helicase activity, preventing the enxymatic seperation of double - standard DNA & interfering with replication and transcription. Epirubicin is also involved in oxidationreduction reactions by generating cytotoxic free radicals.

Methotrexate (formerly Amethopterin) is an antimetabolite used in the treatment of certain neoplastic diseases, severe psoriasis, and adult rheumatoid arthritis. Chemically methotrexate is N-[4-[[(2, 4-diamino-6-pteridinyl) methyl]methylamino]benzoyl]-L-glutamic acid

Pemetrexed disodium heptahydrate has the chemical name L-Glutamine acid, N-[4-[2-(2-amino-4, 7-dihydro-4-oxo1H-pyrrolo[2, 3-d]pyrimidin-5-yl)ethyl]benzoyl]-, disodium salt, heptahydrate. It is a white to almost-white solid with a molecular formula of C20H19N5Na2O67H2O and a molecular weight of 597.49.

Tamoxifen, a nonsteroidal antiestrogen, is a triphenylethylene derivative with both estrogen antagonist on breast tissue and in the CNS and as an estrogen agonist on endometrium, bone and lipids. Tamoxifen and at least several of its metabolites compete with estradiol for binding to cytyplasmic estrogen receptors in tissues such as breast, uterus, vagina, anterior pituitary, and tumors containing high concentrations of estrogen receptors.

Cytarabine Injection, an antineoplastic, is a sterile isotonic solution for intravenous and subcutaneous use, which contains no preservative and is available in 20 mgmL (1000 mg50 mL) Pharmacy Bulk Package. A Pharmacy Bulk Package is a container of a sterile preparation for parenteral use that contains many single doses. The contents are intended for use in a pharmacy admixture program and are restricted to the preparation of admixtures for intravenous infusion. Each mL contains 20 mg Cytarabine, USP and the following inactive ingredients: sodium chloride 0.68% and Water for Injection q.s. When necessary, the pH is adjusted with hydrochloric acid andor sodium hydroxide to a target pH of 7.4. Each vial contains approximately 5.82 mEq sodium

Carboplatin injection is supplied as a sterile, aqueous solution available in 50mg5ml, 150mg15ml, 450mg45ml or 600mg60ml multi-dose vials containing 10mgml of carboplatin for administration by intravenous infusion. Each ml contains 10mg carboplatin and water for injection, usp. Carboplatin is a platinum coordination compound that is used as a cancer chemotherapeutic agent. The chemical name for carboplatin is platinum, diammine [1, 1-cyclobutane-dicarboxylato (2-)-0, 0’]-, (sp-4-2), and has the following structural formula: