Automatic Injectable Powder Filling with Rubber Stoppering is a compact model used for filling Stoppering of Dry Powder Injectable in to vials.

The incoming dry container sterilized are fed through the Un-scrambler and suitably guided on the moving delrin flat conveyor belt at the required speed of the correct placement below powder wheel.

The sterilized powder is stored in powder hopper is agitated by pair of mechanical agitators for maintaining consistency and uniform bulk density. The powder wheel having eight ports rotates at the pre determined speed below the powder hopper with practically no clearance. Powder wheel consist of Piston in each port and behind the powder wheel vacuum plate is provided there is no clearance between powder wheel and vacuum plate due to back spring pressure. Precise volume of powder is sucked in to the port of powder wheel during vacuum according to the piston length different fill size can be achieved. The excess powder is doctored off by a doctor blade. Doctor blades can be adjusted from outside also without removing powder hopper. When powder wheel indexes further and remain in the port due to the vacuum till it reaches just vertically above the container. The time dose of Compressed air (Nitrogen Gas), sterilized low pressure air sequentially flushes out powder from the port of powder wheel in to the container one by one.

The filled container is immediately separated on the conveyor by vial separator and moves further for Stoppering operation. (Different grooves separator can be used which depends on the container diameter or multiple dosing systems).

The sterilized, siliconised, rubber stoppers stored in the vibrator bowl moves to vibratory bowl and stacked vertically in the rubber stopper chute. The container is hold firmly between pair or timing belt to pickup rubber stopper from exit end of the chute. Further the container is passed between two pressing roller for tight fit fixing of rubber stopper.

Pressure Filling Machines are among the most popular of fillers due to the fast fill rate possible by pumping liquid right into the bottle. This saves both time and space since fewer heads are needed per any given rate of production. Furthermore pressure fillers are cost friendly to startups so long as it is compatible with the products to be filled. Very foamy liquids that are slow to settle out the foam can be run, but the pump speeds must be slowed dramatically. Another drawback is any product that has suspended solids because they foul the seals or in the case of some abrasive hand cleaners eat them up. But overall pressure filler is highly recommended for light to medium viscosity products up to the consistency of lighter hair shampoos.

Pressure fillers in rotary compact semi automatic and linear models give high performance and Uniform level fill for accurate volume or as per customer requirements

Monoblock pre Filled Syringe filling and Stoppering machine Model - CPPFS is very compact and elegant PLC based GMP model for automatic filling and Stoppering operation of pre filled syringe.

Operator has to keep a nest (tray) of 100 pre filled syringes over the SS jig. Then he has to put a jig to filling magazine and start the machine to filled syringes.

Operator has to keep a nest (tray) of 100 pre-filled syringes over the SS jig. Then he has to put a plugs tray with suitable stoppers over the SS-316 plug tray. Then after he has to close the evacuation and Stoppering chamber. Now he can start the machine.

Automatic Filling cycle start one by one as per the programmed Stoppering cycle mentioned as under. 100 stoppers are plugged into the pre-filled syringes precisely after vacuum hold cycle. Now last cycle of nitrogen flushing with vacuum break completes the Stoppering operation.

PROGRAM CYCLE FOR EVACUATION AND STOPPERING

SALIENT FEATURES:

UTILITIES

PERFECT SYNCHRONIZATION OF PLC