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Anti - Cancer

Our Complete range of products are Melphanan Tablets, Erlotinib Tablets, Geftinib Tablets and Exemestane Tablets.

Melphanan Tablets

  • Min. Order (MOQ) 10 Strip

We are offering melphanan tablets. Melphalan is a bifunctional alkylating agent which is active against selective human euplastic diseases. Melphalan is a bifunctional alkylation agent. Formation of carboniumintermediates from each of the two bis-2-chloroethyl groups enables alkylationthrough covalent binding with the 7-nitrogen of guanine on dna, cross-linking two dna strands and thereby preventing cell replication.

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Erlotinib Tablets

  • Min. Order (MOQ) 10 Strip

erlotinib is an epidermal growth factor receptor/human epidermal growth factor receptor type 1 tyrosine kinas inhibitor. erlotinib tablet potently inhibits the intracellular phosphorylation of egfr. egfr is expressed on the cell surface of normal cells and cancer cells. the potent effectiveness of erlotinib in blocking egfr-mediated signalling in these egfr mutation positive tumours is attributed to the tight binding of erlotinib to the atp-binding site in the mutated kinas domain of the egfr. due to the blocking of downstream-signalling, the proliferation of cells is stopped, and cell death is induced through the intrinsic apoptotic pathway. tumour regression is observed in mouse models of enforced expression of these egfr activating mutations. erlotinib dosing information usual adult dose for non-small cell lung cancer: 150 mg orally once a day duration of therapy: until disease progression or unacceptable toxicity uses: first-line treatment of patient with metastatic non-small cell lung cancer (nsclc) whose tumors have epidermal growth factor receptor (egfr) exon 19 deletions or exon 21 (l858r) substitution mutations maintenance treatment of patient with locally advanced or metastatic nsclc whose disease has not progressed after four cycle of platinum-based first-line chemotherapy. erlotinib tablets side effects get emergency medical help if you have any signs of an allergic reaction to erlotinib: hives; difficult breathing; swelling of your face, lips, tongue, or throat. do not use erlotinib at once if you have: sudden chest pain discomfort  wheezing  dry cough  feeling short of breath  

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Geftinib Tablets

  • Min. Order (MOQ) 10 Strip

gefitinib is a selective small molecule inhibitor of the epidermal growth factor receptor tyrosine kinase and is an effective treatment for patients with tumours with activating mutations of the egfr tyrosine kinas domain regardless of line of therapy. this drug used for the treatment of locally advanced or metastatic non-small cell lung cancer, after failure of both platinum-based and taxane-based chemotherapies. geftinat 250mg tablets is manufactured by natco pharma india and contains the drug gefitinib i.p 250 mg in each tablet that is a targeted therapy.gefitinib tablets which classified as a signal transduction inhibitor. gefitinib i.p 250mg inhibits egfr tyrosine kinase by binding to the adenosine triphosphate (atp)-binding site of the enzyme. mechanism of action and pharmacodynamic effects the epidermal growth factor and its receptor have been identified as key drivers in the process of cell growth and proliferation for normal and cancer cells.egfr activating mutation within a cancer cell is an important factor in promotion of tumour cell growth, blocking of apoptosis, increasing the production of angiogenic factors and facilitating the processes of metastasis. no clinically relevant activity has been shown in patients with known egfr mutation-negative tumours. drug class and mechanism gefitinib tablet is a drug that is used to treat several types of lung cancer. it works by preventing lung cancer cells from growing and multiplying. many cells, including cancer cells, have receptors on their surfaces for epidermal growth factor (egf), a protein that is normally produced by the body and that promote s the growth and multiplication of cells. when egf attaches to epidermal growth factor receptors (egfrs), it causes an enzyme called tyrosine kinas to become active within the cells. tyrosine kinas triggers chemical processes that cause the cells, including cancer cells, to grow, multiply, and spread. gefitinib attaches to egfrs and thereby blocks the attachment of egf and the activation of tyrosine kinas. this mechanism for stopping cancer cells from growing and multiplying is very different from the mechanisms of chemotherapy and hormonal therapy. gefitinib was approved by the fda in may 2003. uses of geftinib tablets gefitinib is prescribed to treat lung cancer. it is proven to help to slow down cancerous cells growth and reproduction. it works by blocking a certain protein enzyme called tyrosine kinase. dosage and administration most patients who have been prescribed geftinib tablets are told to dose once a day, with or without food. unless otherwise instruct by your physician, tablets should always be swallowed whole and should not be chewed, crushed or dissolved in liquid.  

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Exemestane Tablets

  • Min. Order (MOQ) 10 Strip

exemestane is an oral steroidal aromatise inhibitor used in the adjuvant treatment of hormonally-responsive breast cancer in postmenopausal women. an aim in the treatment of hormone-receptor-positive patients in preventing recurrence is to lower estrogen levels that this breast cancer thrives on. the main source of estrogen is the ovaries in premenopausal women, while in post-menopausal women most of the body's estrogen is produced in the adrenal gland from the conversion of androgens into estrogen by the aromatase enzyme. exemestane tablets are an irreversible, steroidal aromatase inactivator, structurally related to the natural substrate androstenedione. pharmacokinetics exemestane is an irreversible selective aromatase inhibitor which acts as a false substrate for the aromatase enzyme, forming an intermediate that binds irreversibly to the active site causing its inactivation. it also lowers circulating oestrogens in estrogen-dependent breast carcinoma. uses of exemestane tablets exemestane is an oral medication prescribed to treat breast cancer in post-menopausal women. it operates by reducing estrogen levels to stop or slow the growth of tumours that are thought to use this hormone to grow. dosage and administration strictly use exemestane as prescribed by your physician to get the best results. your dosage and frequency of administration will be determined based on your symptoms and current health condition. swallow the tablets whole and unaltered with a full glass of water after a meal or snack to prevent an upset stomach. do not alter the form of the medication by chewing, splitting, or dissolving them in water as this can destroy the contents or change their effects. precautions exemestane tablets should be used by women who have not gone through menopause, pregnant, breastfeeding, or lactose intolerant. also disclose if you have osteoporosis, decreased liver function, or decreased kidney function to make sure any necessary adjustments are made to your dosage.

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  • Mr. Raj
  • No. 56, VT. Nagar Society, Nr Sarthana Jakatnaka, Subhashnagar Road, Surat, Gujarat - 395006, India