Nagpur, Maharashtra, India
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MICCEL – CMC
Microcrystalline Cellulose & Carboxymethyl Cellulose Sodium IP/USP
Solution for Suspensions, Lotions and Creams :
MICCEL CMC is the mixture of microcrystalline cellulose and carboxymethyl cellulose Sodium various ratio depend on application. We produce following types of grades.
Specification
| Test | Specification |
|---|---|
| Description | Tasteless, odoriess, white, coarse to fine powder. |
| Solubility | Swells in water, producing, when dispersed, a white, opaque dis or gel Insoluble in organic solvents and in dilute acids. |
| Identification | |
| Test-A | A white opaque, dispersion is produced that does not settle on Standing. |
| Test-B | Each drop forms a white, opaque globule that does not disperse standing |
| Test-C | No blue or purplish blue color produced. |
| Assay, % CMC sodium | Refer chart |
| Impunities | |
| Residue on ignition% | NMT 5.0 |
| Heavy Metals, pg/g | NMT 10 |
| Specific Test | |
| Viscosity-Rotational Method, % of that stated on the label, In Cps | 60.0-140.0 |
| pH | 6.0-8.0 |
| Loss on drying, % | NMT 8.0 |
Grade Wise In House Specification
| Test | MiCCEL CMC – 501 | MICCEL CMC – 581 | MICCEL CMC – 591 | MICCEL CMC |
|---|---|---|---|---|
| Viscosity ,cps(by Labman Viscometer, Model – LMDV 200L, Spindle no. 2) | Between 70 and 170 (2,1% Solid) |
Between 70 and 170 (2,1% Solid) |
Between 40 and 95 (1.2% Solid) |
Between 50 and120 (2.6% Solid) |
| Retention on 60 # (%) | NMT 0.1 | NMT 0.1 | NMT 0.1 | NMT 0.1 |
| Retention on 200 # (%) | NMT 40 | NMT 35 | - | - |
| Retention on 325 # (%) | - | - | NMT 45 | NMT 50 |
Silicified Microcrystalline Cellulose – USP
Solution for Optimum CompatibilitySilicification of MCC increased physical properties such as true density, Hausner ratio, porosity, ejection force and specific surface area. Other properties such as bulk and tap densities were reduced due to the amorphous and light character of fumed silica.
MICCEL S is the mixture of microcrystalline cellulose and colloidal silicon dioxide (MCC/CSD at 98:2 ratio) and most compactible grade of SMC with flow characteristics similar to doubling the parties size of MCC.
Specification
| Test | Specification |
|---|---|
| Description Solubility |
White or almost white, very fine to moderately fine powder. It is a free-flowing material. Slightly soluble in sodium hydroxide solution (1 in 20); practically insoluble in water, in acetone, in ethanol, in toluene, and in diluted acid. |
| Identification | |
| Test-A (IR Absorption) Test-B Test-C Test-D(silica dispersion uniformity test) |
Should be comply The substance takes on a violet-blue color should be produced. A deep yellow color is produced NMT 0.02 |
| Impurities | |
| Heavy Metals, µg/g | NMT 10 |
| Specific Tests | |
| Residue on Ignition, % | 1.8 – 2.2 |
| Microbiological Analysis | |
| Total Aerobic Microbial Count, CFU/g Total Combined Molds and Yeasts Count, CFU/g Escherichia Coli/g Pseudomonas Aeruginosa/g Staphylococcus Aureus/ g Salmonella Species/ 10g |
NMT 1000 NMT1000 Should be absent Should be absent Should be absent Should be absent |
| Conductivity, µS/cm pH Loss on Drying, % Degree of Polymerization Bulk Density Particle Size Distribution Water Soluble Substances, % Ether Soluble Substances, % |
NMT 75 5.0 – 7.5 NMT 7.0 NMT 350 Refer chart Refer chart NMT 0.25 NMT 0.25 |
Grade Wise In House Specification
| Test | MICCEL S-101 | MICCEL S-102 | MICCEL S-112 |
|---|---|---|---|
| Loss on drying (%) | NMT 7.0 | NMT 7.0 | NMT 1.5 |
| Bulk Density, g/ml | 0.28 to 0.33 | 0.25 to 0.37 | 0.25 to 0.37 |
| % Retention on 60 # | NMT 1 | NMT 8 | NMT 8 |
| % Retention on 200# | NMT 30 | NLT 45 | NLT 45 |
MICCEL CMC MICCEL CMC is the mixture of microcrystalline cellulose and carboxymethyl cellulose Sodium various ratio depend on application. We produce following types of grades.
Microcrystalline Cellulose & Carboxymethyl Cellulose Sodium IPUSP
Solution for Suspensions, Lotions and Creams :
