Alpha arbutin vitamin b3 glutathione vitamin c sasaki glutathione alpha arbutin vitamin c and b3: how to apply: after face wash or cleaning, apply 1 or 2 drops of serum massage gently till absorbed by the skin use twice a day- morning and night results visible within two or three days sasaki glutathione alpha arbutin vitamin c and b3: benefits: sasaki glutathione alpha arbutin vitamin c and b3 serum gives number of benefits such as: removes blackheads and pimples removes blemishes and dark spots suits all skin types no side effects.