vyvanse (lisdexamfetamine) is a central nervous system stimulant. It affects chemicals in the brain and nerves that contribute to hyperactivity and impulse control. vyvanse is used to treat attention deficit hyperactivity disorder (adhd) in adults and in children who are at least 6 years old. vyvanse may also be used for other purposes not listed in this medication guide. do not use vyvanse if you have taken an mao inhibitor in the past 14 days. A dangerous drug interaction could occur. Mao inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. vyvanse is a drug of abuse and may be habit-forming. Keep track of the amount of medicine used from each new bottle. You should be aware if anyone is using your medicine improperly or without a prescription. Using this medication improperly can cause death or serious side effects on the heart. you should not use vyvanse if you are allergic to lisdexamfetamine. do not use vyvanse if you have taken an mao inhibitor in the past 14 days. A dangerous drug interaction could occur. Mao inhibitors include isocarboxazid, linezolid, methylene blue injection, phenelzine, rasagiline, selegiline, tranylcypromine, and others. some stimulants have caused sudden death in people with serious heart problems or congenital heart defects. Tell your doctor if you have heart disease, heart rhythm disorder; coronary artery disease (hardened arteries); or history of heart attack. to make sure this medicine is safe for you, tell your doctor if you have high blood pressure; peripheral vascular disease such as raynaud's syndrome; a personal or family history of mental illness, psychotic disorder, bipolar illness, depression, or suicide attempt; or if you take an antidepressant.