Rabies Vaccine

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Freeze-Dried Rabies Vaccine For Human Use

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Rabies vaccine is a freeze-dried preparation made from the inactivated rabies fixed virus. The virus grows in vero cells. After cultivation, harvest and concentration, the virus suspension is inactivated, purified and then lyophilized to make the vaccine after the addition of a suitable stabilizer. It is used to prevent rabies.1 basic requirementsthe facilities, source and subsidiary materials, water. Apparatus and animals used for production and control tests shall comply with the requirements set forth in the general notices.2 manufacturing2. 1 cell substrates for vaccine production vero cells shall be used for the vaccine production2. 1. 1 management and control tests on cell substrates.it complies with the requirements for preparation and control of animals cell substrates used for production of biologics. The maximum passage number of the cells from cell banks at every level shall not exceed the approved limit.2. 1. 2 cell substrate preparationthe cells from one or more containers of the working cell bank are resurrected to expand by serialsubculture up to a quantity enough for making one lot of vaccine. The quantity of the cells can bedefined as a cell batch. During the subculture of the cells, trypsin or other suitable digestion solution at an appropriate concentration is added onto the monolayer cell cultures to disperse cells. The dispersed cells are suspended evenly with suitable growth medium and distributed into culture bottles. Incubate the cells at 370c to form c

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Prevent Rabies Vaccine

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Rabies Vaccine (Vero cell) for Human Use, Freeze-dried [Description] The vaccine is a freeze-dried preparation made fromthe inactivated rabies fixed virus. The virus growsin Vero cell cultures. After cultivation andharvest, the virus suspension is concentrated, inactivated, purified, and lyophilized to make thevaccine after the addition of a suitable stabilizer. The product looks like a white crisp cake. Afterreconstitution, it shall turn into a transparentliquid without containing any preservatives. Active constituent : Inactivated rabies fixed virus.Subsidiary materials: All of the subsidiarymaterials approved shall be listed. Diluent: Sterile water for injection [Eligibles] If a person is bitten or scratched by a rabid dog orother rabid animals, regardless of age or sex, the wounds shall be cleaned immediately (Flush thewounds repeatedly with clean water or soap water and then apply iodine tincture or ethanol repeatedlyto the wounds. ), and the exposed person shall beinoculated with the vaccine according to thepostexposure schedule as soon as possible. The persons at risk of contacting rabies virus (such asveterinarians, animal breeders, forestry workers, workers in slaughterhouse and staffs in rabieslaboratory) shall be immunized following the pre-exposure immunization schedule. [Action and use] The product can induce immunity against rabies virus in recipient

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Medical Prevent Rabies Vaccine

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If a person is bitten or scratched by a rabid dog or other rabid animals, regardless of age or sex, the wounds shall be cleaned immediately (flush the wounds repeatedly with clean water or soup water, followed by applying iodine tincture or ethanol for several times), and the exposed person shall be inoculated with the vaccine according to the post-exposure schedule as soon as possible. The person at risk of contacting rabies virus (such as veterinarians, animal breeders, forestry workers, workers in slaughterhouse and staffs in rabies laboratory) shall be immunized following the pre-exposure treatment schedule. [Function and use] The preparation can induce immunity against rabies virus in recipients following immunization. It is used to prevent rabies in human. [Specifications] 0.5 ml of reconstituted vaccine per container. 0.5 ml per single human dose. The potency of the vaccine shall be not less than 2.5 IU. [Administration and dosage] Reconstitute the freeze-dried vaccine with the enclosed sterile water for injection as the stated value, and shake the container thoroughly before use. (2) Inject i. m. the vaccine at deltoid insertionarea of the upper arm. For young children, inoculate the vaccine in themuscle at anteroexternal aspect of the thigh. (3) Postexposure immunization schedule: Normally one dose of the vaccine shall beadministered to the exposed person on days 0 (thefirst day i. e. that very day), 3 (the fourth day, analogically

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