IKON PHARMACEUTICALS

Shimla Bypass, Dehradun, Uttarakhand

Drug for bipolar disease^{1, 2}

• Has shown to achieve the clinical response against manic symptoms up to 63%³
• Reduces suicidal risks more than 8-fold¹
• Shows long-term therapeutic response in both typical and a typical features of bipolar disease⁴
• Supports neural plasticity, provides neuroprotection and balances neuronal activities⁵
• Exhibits better efficacy and safety along with faster relief than chlorpromazine6 and olanzapine⁷

Details :

• Selective, long-acting, nonsedating, second-generation antihistamine'
• Significantly reduces wheal and flare responses to allergens²
• Reduces the nasal symptoms occurring after nasal provocation with grass pollen²
• Possess a favorable risk:benefit ratio for sedation and do not impair cognitive or psychomotor performance, including driving ability²
• Produces a dose-dependent inhibition of the cutaneous reaction to histamine and antihistaminic effect which lasts for more than 48 hours²

Details :

• Centrally acting muscle relaxant that exhibits anti spastic and analgesic activity¹
• Stabilizes nerve membrane and inhibits pathologic mono- and poly-synaptic reflex activity¹
• Works by blocking N-type Ca2+ channels and voltage-gated Na+ channel conductance¹
• Offers superior efficacy as compared to baclofen²

In muscle spasms i neck injuries strains, sprains and injuries of the back.

Selective aromatase inhibitor that works by

• Preventing the conversion of androgens to estrogen
• Thus releasing the hypothalamo-pitutary axis from the negative feedback of estrogen
• Resulting in an increase of Follicle stimulating hormone from anterior pituitary

FOLLICLE GROWTH¹

• Increases follicular sensitivity to FSH through amplification of FSH receptor gene expression²
• Devoid of any anti estrogenic peripheral action unlike Clomiphene Citrate (CC)¹
• Effective for ovulation induction and pregnancy in cases of CC resistance³
• Has shown to produce statistically significantly higher mono-follicular development and pregnancy rate in infertile PCOS women²

Details :

• A barbiturate derivative that exhibits potent sedative and anticonvulsant activity²
• Works by acting on GABAA receptors, thereby prolonging the action of GABA¹
• Diminishes excitatory neurotransmission by reducing the effects of glutamate³
• Possesses an inhibitory effect on adult brain' and act as a non-selective central nervous system depressant⁴

Details :

• Potent, anti-inflammatory agent with potency 1.25 times compared to prednisolone¹
• Acts by inhibiting the activation of T cells²
• Offers low tendency to induce sodium and water retention compared to hydrocortisone¹
• Accelerate resolution of asthma attacks without significant suppression of adrenal function³

Indication :

• Inflammatory Diseases Like
• Arthritis
• Lupus
• Psoriasis
• Ulcerative Colitis
• Allergic
• Disorders

Provides symptom improvement and reduction of relative risk of BPH clinical progression in men with enlarged prostates¹

Dutasteride

• Dual inhibitor of both type I and type II 5 a-reductase, inhibits the conversion of testosterone to dihydrotestosterone (key contributor of AGA)²
• Reduce serum DHT levels by 95%, leading to a reduction of approximately 94-97% of DHT levels in the prostate¹

Tamsulosin

• Selective alpha 1 adrenoceptor antagonist with specificity for prostatic alpha 1 adrenoceptors⁴
• Improves nocturia by decreasing the nocturnal urine volume⁴

FDA approved adjunctive therapy for partial-onset seizures¹

• Third-generation antiepileptic drug that selectively enhances the slow inactivation of voltage-gated sodium channels²
• Possess favourable pharmacokinetic profile with low protein binding and low potential for drug-drug interactions3
• Can be considered as an alternative to Fosphenytoin in the treatment of nonconvulsive seizures (NCS)⁴
• Offers good tolerability and safety for use in status epilepticus (SE)⁵