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We offer the best product range of Containment Isolators.

Containment Isolators

Containment Isolators
Description:

Isolation technology has shown tremendous potential due to various technological development such as transfer, filtration, granulation, ventilation systems etc. Isolator means a physical barrier between a process and its operator. An isolator is closed system whose size and features very according to the type of application. With in this environment simple and complex operation can be carried out, either manually or automatically. These operations can be conducted in controlled atmospheres, at particle or microbiological levels. Control system, quality of air and type of gases used inside the isolator those are importance things for the successful implementation of isolation system.

Isolator Applications Requirements for containment Processing

  • Generally operated under negative pressure to ensure max. Operator safely.
  • Negative pressure isolator is basically used for powder handling process and highly disperses products.
  • Well Designed capacity of motor and blower as per sufficient air flow requirement.
  • They must not exchange air with the surrounding environment (except through a HEPA filter)
  • Equipped with nitrogen supply if required
  • Negative pressure of-100Pa, Pneumatically controlled interlocked isolator door after start of operation.
  • Visual display indicates permanent status of the isolator.
  • Radii in the isolator chamber>15mm
  • Tightness test before each process
  • Push-Push system for exhaust air filters
  • Integrated rapid transfer ports(RTP) for loading and discharging without compromising the surrounding
  • Negative isolator basically used for sampling, Dispensing, Quality checking, Product charging, Filtration, Drying, Milling, Sieving, Blending, Solution Preparation, Weighing and R& D purpose.

Class Hourly leak rate
Rh h-1
Pressure
integrity
Test methods
1 <5x104 High Oxygen method, pressure
change method or parjo
method
2 <2.5x102 Medium Oxygen method, pressure
change method or parjo
method
3 <104 Low Oxygen method, pressure
change method or
constant pressure Method
4 <103   constant pressure Method

 

OEL (OPERATOR EXPOSAL LIMITS) CATEGORIES:
OEL LIMITS: Products are classified according to hazards level that correspond to these five OEL level as shown in the chart below:
Categories Hazard Description  
OEL 1 Harmful, and/ or low pharmacological
activity
1000-
5000ug/m3
OEL 2 Harmful, and moderate
pharmacological activity
100-1000ug/m3
OEL 3 Moderately toxic and/ or high
pharmacological activity
10-100ug/m3
OEL 4 Toxic and/ or very high pharmacological
activity
1-1ug/m3
OEL 5 Extremely Toxic and /or extremely high
pharmacological activity
<1ug/m3















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