Chemical Reactors & Process Tanks

We offer a complete product range of Single-Use Laboratory Bioreactor and Pilot Scale Bioreactors

Single-Use Laboratory Bioreactor

The EDF-5.4 monoblock can be adapted for single use bioreactor control. For example, we have expierence in application of single use vessels from CerCell (Danmark). CerCell has configurable vessels of different volumes (0.5 to75 liters). These vessels are equipped with all necessary accessories to provide fermentations of different microbial cultures. An important advantage of these vessels is the possibility to achieve high mixer rotation speeds. For example, 7.5 liter bioreactor, equipped with 3 ruchton turbines, can achieve mixer rotation speed up to 1500 rpm. In SUB it is possible to apply both single use and sterilizable pH and pO2 sensors.The application of SUB has following advantages: Decreases the risk of contamination;Eliminates the necessity to acquire and maintain the infrastructure for the processes (cleaning and sterilisation), which can be critical for validation;Simplifies and reduces validation costs;Reduces the costs of labor expenditures for the preparation operations (assembling - disassembling, cleaning and sterilization);The possibility to develop the fermentation processes according GMP requirements.

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Pilot Scale Bioreactors

We offer stainless steel bioreactors from 20 to 15000 liters, as well as bioreactor lines, including other technological vessels. An autonomous bioreactor consists of 3 main parts: Bioreactor vessel;Technological stand;Control cabinet, including PLC. The connections between the bioreactor vessel and the technological stand are implemented with the help of flexible parallel wrapped stainless steel tubes. To ensure fully automated in-situ sterilization process, it is necessary to install pneumatically controlled membrane valves in the bottom, the inlet of a sparger and the lid of the vessel.The bioreactor vessel The fully equipped stainless steel bioreactor vessel (sterilizable in place) with upper or lower magnetic drive for agitation with 2 3 standard rushton turbines (pitched blade or marine mixer optionally). For all vessels H:D is in the range of 1:1.5 to 1:3. It can be specified in certain limiting sizes. For all vessels the maximal design pressure inside the vessels 3.0 bar, in jacket 3.5 bar. Maximal temperature 1400C. Inner vessel wall: surface roughness lower than 0.4m. Outer vessel wall: surface roughness 0.63 m (pickled & passivated). The material of the parts, contacting with product is stainless steel 316L. For parts, not contacting with product (for example, jacket), stainless steel 304. All bioreactors have insulation over the jacket. The outside surface of insulation is covered by stainless steel 304.

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