Other Products / Services #6737270

Tamilnadu Test House is a well-known lab in the field of Chemistry, Microbiology, and Biotechnology. We offer services in LCMS, GCMS, HPLC, GC, FT-IR, AAS, TGA, DSC, UV-Vis, and in all spectroscopy, and chromatography instruments.

We are offering the following services in Cosmetic

1.Test the cosmetic Products as per BIS standards and certify the Products

2.Chemical analysis of Cosmetic Products

3.Microbial analysis and Contamination of the Products

4.Heavy metal contamination

5.Organic certification of the Products

6.Allergen testing as per IFRA Standards

7.Comparative study of your product with international brands

8.Shelf life study

9.Preservative efficacy study

Bio TechnologyBio Assay & ScreeningTamilnadu Test House provides testing services for a wide range of enzyme assays, immuno assays, cell-free assays and cell based assays for the biologics & biosimilar development across all stages of discovery and development, starting with R & D, Preclinical and Clinical phases to lot release, in-process validation and stability testing. We provide essential testing that establishes the safety and potency of biopharmaceuticals as well as determines pharmacokinetic and pharmacodynamic profiles. Read more Batch & Lot release assays for BiologicsPotency testing is critical for product activity comparison, the regulatory submission, and batch or lot release of Bio-pharmaceuticals. Most importantly, bio similar products need to be demonstrating the product efficacy and manufacturing batch consistency.Read more Custom Cell Protein (HCP)Tamilnadu Test House are experts in the development of high sensitive Host Cell Protein (HCP) assays for therapeutic proteins and antibodies. As per the current Indian regulatory guidelines, biopharmaceutical companies should develop product specific HCP assays to evaluate the therapeutic protein purity. Read more Cell Biology, Protein Biology & ImmunologyIn vitro Drug Screening Assays using Mammalian Cells.Read more Confocal MicroscopyBacterial Viability in Dentinal TubulesRead more

The amount of residual solvents introduced while processing concentrates are determined by tnth with the help of certain validated testing methods. We monitor the ppm levels of solvents which help to identify raw materials & products that are free from harmful contamination. We conduct tests for residual solvents using gc-fid coupled with headspace sampling as per usp 467 for residual solvents in pharmaceuticals. We have an unique method to indentify the light gases which are not included in usp 467. We offers testing services for propane, isobutane, n-butane, isopentane, n-pentane, isopropanol, ethanol, acetone, hexane and naphtha all in one assay.Usp and ich q3c residual solvents determination.57 solvents are listed under class 1 (unacceptable due to toxicity), class 2 (solvents without sufficient toxicological data) or class 3 (least toxic, ideal solvents) and , all of these need to be screened and if identified needs to be quantified under the proposed usp (& existing ep) guidelines. Tamilnadu test house compliance laboratories offers expert testing services for the analysis of residual solvents which are listed below as class 1 residual solventsbenzenecarbon tetrachloride 1, 2-dichloroethane1, 1-dichloroethene 1, 1-dichloroetheneclass 2 residual solvents (usp mixture a and b)acetonitrilechlorobenzene chloroform cyclohexane 1, 2-dichloroethene 1, 4-dioxane hexanemethanol methylbutylketone methylcyclohexane methylene chloride nitromethane tetrahydrofuran tetralintoluene trichloroethylene xylenes usp class 2 direct injection (usp mixture c performed upon request)formamide2-ethoxyethanol 2-methoxyethanol ethylene glycoln-methylpyrrolidone sulfolane pyridine

Elemental analysis by aas and icp-oesprecious metal analysistamilnadu test house offers testing in precious metal like gold and silver by using fire assay method. Tamilnadu test house also analyse the gold and silver content in nanotechnology samples, collagen samples, ayurvedic products and animal house study samples.Trace metal analysis by aas and icp-oestrace metal analysis of elemental impurities is very critical for pharma products before market launch. The elemental composition of alien metals helps defining the product purity and quality.Metal contaminations have been observed in drugs expected for use by people and creatures. Drug articles incorporate dynamic pharmaceutical ingredient (api), excipients, drugs and dietary supplements alongside their ingredients. Some metals viz. Arsenic, mercury, cadmium and lead are lethal at low levels and ought to be checked to ensure safety of consumers. The source of metal impurities might be from those added to the process (such as catalyst) or those derived from the process itself, or maybe contaminants from input material or reagents.The usp under the general chapter (231) specifies the test procedure for identifying metal impurities such as aluminium, arsenic, iron, lead, and mercury. Usp (231) is a qualitative or semi quantitative limit test. It helps identifying the metallic impurities using sulphide ions which results in a coloured precipitate. The standard comparison assists in evaluating exceeding specified limits. The sample preparation schemes used in the analysis are:

Raw materials and excipients testingthe drug raw materials and excipients are tested according to latest pharmacopoeial (usp, bp, ep, ip, jp) procedures. The following are the tests: identification teststrace metal analysis using aas and icp-ms techniquesorganic volatile impurities & residual solvents as per usp procedureheavy metalspharmaceutical grade water testing as per usp and bp procedureswe also offer test procedures for non-pharmacopoeial raw materials and excepients.,

We offer the best results in agricultyural testing. Our testing includes soil, plant, water and manure analysis. Our turnaround time and precise resultshas helped farmers, crop input dealers, research organizations and many companies. The information provided by us enhances crop production, maximizes economic returns and minimizes the environmental impact on soil and water. AgricultureSoil TestingA survey was conducted amongst farmers few years ago and when asked whether soil testing is something they should use to improve soil fertility and for raising better crops. Almost 82% of them said Yes and almost 28 % of them said that they have used soil tests. Read more NematodesNematodes are microscopic creatures which are worm like living in the soil and feed primarily on the roots of plants. They almost there in every soil and if the soil is coarser means more Nematodes. Read more Water AnalysisKnowing the quality of water is very essential. Whether the water is being used for irrigation, human consumption, fish growth or livestock suitability, Tamilnadu Test House will help you to analyse the quality of water. Read more FertilizerIt is good to know the analysis of the fertilizer being purchased or manufactured. Manufacturers should be rest assured that the claimed contents are compliant to regulatory standards. Failing to meet will result in serious problems. Be sure and get the fertilizer product analyzed. Read more Feed AnalysisHaving your feed tested is a way of ensuring your livestock are consuming the adequate nutrients they need in their diet. Poor nutrition can affect not only the productivity of the animal, but also its health and behavior. Forage and feed sampling is an essential tool in determining your animal feed quality.Read more

Method development and validationanalytical method development and validation as per ich guidelinesdevelopment of stability-indicating methodsimpurity identification and quantificationmethod development and validation for heavy metal estimation by icp oes/mscleaning validationsdissolution studiesextractable and leachable studiesstability studies as per ich guidelinesfor all your pharmaceutical development activities a reliable analytical data is very vital. To achieve this, an analytical method development and validation is very critical. Across the industry method development and validation are costly and labour intensive. At tnth we combine knowledge and experience along with advanced instrumentation, to develop efficient, accurate, reliable and robust analytical methods at affordable cost.

Nuclear magnetic resonance (bruker nmr ultrashiled 400 mhz):1d proton, carbon and phosphorus std, water logsy2d cosy, tocsy, roesy, noesy, dosy; dosy-tocsy (3d), rdc, t1, t2, t1p relaxation2d hmqc, hmbc & hsqc analysis for h-c and h-p correlations, peptides and metabolites such as atp, adp and nadp.

Tamilnadu test house offers a wide array of testing services for both large and small companies. We are also favored by small companies and can help your company decide which test is appropriate and necessary, given your budget and overall manufacturing operation.We test the hand sanitizer for its anti microbial efficacy by using minimum inhibitory concentration test (mic test) as well the astm method astm e2315 (standard in vitro time-kill procedure).Tamilnadu test house uses 23 species of bacterial species and one fungal culture for evaluation of bactericidal activity of the hand sanitizer.The 24 microorganism used in the test are mentioned as belowgram-negative bacteria:acinetobacter species (such as a. Baumannii)bacteroides fragilishaemophilus influenzaenterobacter species (such as e. Aerogenes)esherichia coli (first strain)esherichia coli (second strain)klebsiella pneumoniaepseudomonas aeruginosa (first strain)pseudomonas aeruginosa (second strain)proteus mirabilisserratia marcescens

Quality is the most extreme essential thing in the pharmaceutical business as individuals lives are specifically subject to the nature of drugs given to them for the treatment of infections or diseases. This highlights that it is so critical to have a dependable accomplice for testing and accreditation of pharmaceutical products and their ingredients.Tamilnadu test house offers a wide range of pharmaceutical testing & research services which helps in improvement, endorsement, , and make of pharmaceutical raw materials and finished products.Our pharmaceutical lab offers:pharmacopoeial testing based on usp, bp, ep or iptesting based on clients in-house practicesdocumented in-house methods which are validatedmoreover, the organization can create and validate methodologies for use on raw materials, apis or finished products. The research facility has additionally attempted work in support of process & cleaning validation and stability studies for pharma industry. Whether it is normal qc testing, non-routine analysis, research & development projects or consulting, customers can be rest assured that tnth will be responsive, accurate and analytical in its support services.

Tamilnadu test house offers vitamin analysis in wide range for pharmaceutical industries, food supplements, food matrices, animal feed.Tamilnadu test house developed its own method to quantify the vitamin by hplc and also uses aoac, usp and indian pharmacopeia methodsmoa for vitamin testing parameter method principlefat-soluble vitamins vitamin a tnth hplccarotin tnth hplcvitamin d2/d3 (ergocalciferol/cholecalciferol) tnth usp hplcvitamin e tnth hplcvitamin k1 (phyllochinon) tnth, usp hplcwater-soluble vitamins vitamin b1 (thiamin) tnth, usp hplcvitamin b2 (riboflavin) tnth hplcvitamin b6 (pyridoxin &pyridoxamin& pyridoxal) tnth , usp hplcvitamin b12 (cyanocobalamin) aoac, usp mb, hplcniacin (nicotinic acid &nicotinamid) aoac, usp mb, hplcpantothenic acid aoac, usp mb, hplcbiotin tnth, usp mb, hplcfolic acid aoac, usp mb, hplcvitamin c (ascorbic acid & dehydroascorbic acid) tnth, aoac hplcabbreviations used:hplc: high performance liquid chromatographymb microbiological methodtnth: tamilnadu test house methodusp: united states pharmacopeiaaoac: association of official analytical chemistsmatrices validated for standard tests comprise but are not limited to:pharmaceutical finished products (tablets, capsules, syrups)food matricesanimal feedpet foodfood supplementscosmetics

Tamilnadu test house offers asbestos analyses in talcum powder, soil samples, and building materials or demolition debris. Asbestos is a naturally occurring silicate mineral which finds innumerable applications in construction and process industries. However, exposure to environments with high concentrations of asbestos can present occupational hazards.Asbestos is classified as group a, a known human carcinogen which cause lung cancer and mesothelioma and possibly gastrointestinal cancers in humans. Cosmetics can also pose carcinogenic hazards if not formulated with the appropriate ingredients. Talcum powder is one cosmetic ingredient which has been used for centuries. Its primary source is soapstone which is hydrated magnesium stearate with other mineral carbonates and silicates present in minor amounts.Talcum powders can also contain asbestos which is a known carcinogen. Due to its low concentration, its presence does not pose the serious risk due to inhalation but using it in cosmetics directly on the skin can cause cancer over years of regular use.Tamilnadu test house using x-ray diffractometer, to analyse the asbestos content and we can detect in ppb level of asbestos content.