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1 Products availableTacrolimus works by suppressing the immune system to prevent the white blood cells from trying to get rid of the transplanted organ. Tacrolimus is a very strong medicine. It can cause side effects that can be very serious, such as kidney problems. It may also decrease the body's ability to fight infections.
acrolimus (also FK-506 or Fujimycin) is an immunosuppressive drug whose main use is after organ transplant to reduce the activity of the patient's immune system and so the risk of organ rejection. It is also used in a topical preparation in the treatment of severe atopic dermatitis, severe refractory uveitis after bone marrow transplants, and the skin condition vitiligo. It was discovered in 1984 from the fermentation broth of a Japanese soil sample that contained the bacteria Streptomyces tsukubaensis. Tacrolimus is chemically known as a macrolide. It reduces peptidyl-prolyl isomerase activity by binding to the immunophilin FKBP-12 (FK506 binding protein) creating a new complex. This FKBP12-FK506 complex inhibits calcineurin which inhibits T-lymphocyte signal transduction and IL-2 transcription.
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Liraglutide injection is used with diet and exercise to lower blood sugar in people with type 2 diabetes. It is also used to reduce the risk of life-threatening events, including heart attack and stroke, in adults with type 2 diabetes and established heart or blood vessel disease.
Liraglutide injection is in a class of medications called incretin mimetics. It works by helping the pancreas to release the right amount of insulin when blood sugar levels are high. Insulin helps move sugar from the blood into other body tissues where it is used for energy.
Victoza (liraglutide) injection can be given any time of the day or night. It's best to get into a daily routine and use your Victoza at the same time each day. You are less likely to forget it this way. Victoza can be taken with or without food without regards to mealtime.
Liraglutide is used either alone or with other medications, and with a proper diet and exercise program, to control high blood sugar. It is used in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems.
Isotretinoin is used to treat severe, disfiguring nodular acne. It should be used only after other acne medicines or antibiotics have been tried and have failed to help the acne. Isotretinoin may also be used to treat other skin diseases as determined by your doctor.
Isotretinoin capsules are a treatment for severe acne (spots). This medicine can have serious side effects, including side effects that can affect your mental health and sexual health. Isotretinoin capsules must be prescribed and supervised by a specialist doctor.
Most patients who receive oral isotretinoin will be free of acne by the end of 4–6 months of treatment depending on the dose administered.
Isotretinoin is a retinoid and thus it helps to improve and increase the skin turnover. This increases pigment removal through the shed skin and helps to lighten the dark patches.
Pirfenidone is used for the treatment of idiopathic pulmonary fibrosis (scarring of the lungs with an unknown cause). Pirfenidone is in a class of medications called pyridones. It works by blocking the action of a certain natural substance in the body that is involved in causing fibrosis.
Pirfenidone comes as a capsule or a tablet to take by mouth. It is usually taken with food three times a day. Take pirfenidone at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take pirfenidone exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.
Your doctor will start you on a low dose of pirfenidone and gradually increase your dose over a 2-week period.
Your doctor may need to decrease your dose or stop treatment if you experience certain severe side effects. Be sure to tell your doctor how you are feeling during your treatment.
Ask your pharmacist or doctor for a copy of the manufacturer's information for the patient.
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information
Tofacitinib is FDA approved for the treatment of moderate to severe rheumatoid arthritis (RA), psoriatic arthritis (PA), ulcerative colitis (UC), and polyarticular course juvenile idiopathic arthritis (pcJIA). It is a second-generation selective Janus kinase (JAK) inhibitor targeting the JAK1 enzyme.
Tofacitinib is a prescription medication called a janus kinase (JAK) inhibitor. It is a disease modifying anti-rheumatic drug (DMARD), which works by suppressing the immune system. Tofacitinib is available in the form of a tablet (Xeljanz), an extended release tablet (Xeljanz XR) and as an oral solution.
It is used to treat certain inflammatory conditions in people who have already tried tumor necrosis factor (TNF) blockers.
When tofacitinib was approved by the FDA in 2012, it was the first approved JAK inhibitor for the treatment of rheumatoid arthritis and also the first new oral DMARD to be approved for the condition in more than a decade.
What is tofacitinib used for?
Ivermectin cream is a medication that reduces facial redness caused by rosacea. You can apply this cream to your facial skin as directed. Only use a pea-sized amount on each area of your face, including your forehead, chin, nose and each cheek.
IVERMECTIN (eye ver MEK tin) treats rosacea. It works by decreasing inflammation of the skin.
This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.
This medication is for external use only. Do not take by mouth. Wash your hands before and after use. Use it as directed on the label. Apply only to the affected areas of your face. Use a pea-sized amount of cream for each area of your face (forehead, chin, nose, each cheek) that is affected. Spread the cream smoothly and evenly in a thin layer. Keep this medication away from your eyes, mouth, nose, or vaginal opening. Do not get it in your eyes. If you do, rinse your eyes with plenty of cool tap water. Do not use it more often than directed. Keep using it unless your care team tells you to stop.
Talk to your care team about the use of this medication in children. Special care may be needed.
Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.
NOTE: This medicine is only for you. Do not share this medicine with others.
Fenbendazole, [5-(phenylthio)-1H-benzimidazol-2-yl]carbamic acid methyl ester, is widely used to treat pinworms, other helminthes, and a variety of parasitic infections in laboratory animals, livestock, companion animals, and people (1–3). We became interested in fenbendazole when our university veterinarians recommended that all experimental rodents, including uninfected colonies such as ours, be treated with a fenbendazole-containing diet because of pinworm infections in some colonies. Our research uses tumors in rats and mice to evaluate the effects of new regimens for treating solid tumors with radiation and/or anticancer drugs (4–10). As we researched this proposed prophylactic treatment, we became concerned that the fenbendazole-containing chow might compromise our experiments, but also became intrigued by the possibility that this drug might have antineoplastic effects, by disrupting the tubulin microtubule equilibrium, or by altering the viability or radiosensitivity of cells in the hypoxic environments found in solid tumors. Fenbendazole acts on helminthes primarily by binding to tubulin and disrupting the tubulin microtubule equilibrium; its utility as an antiparasitic drug results from differences in the structures of tubulin in mammalian cells and in lower organisms, which lead to its greater binding to tubulin, and therefore greater inhibition of polymerization, in the parasites (11–13). In addition, the limited absorption of fenbendazole from the intestine results in low levels of the drug and its active metabolites in tissue relative to the levels within the gut, to which the targeted parasites are exposed (1, 14, 15). Several widely used anticancer drugs produce their antineoplastic effects by disrupting either microtubule formation (vincristine; vinblastine) or microtubule depolymerization (paclitaxel; docetaxel) (13, 16), suggesting that fenbendazole could have antitumor effects. Some data in the literature support this hypothesis (13). A Fenbendazole-containing diet combined with supplemental high dose of vitamins was reported by Gao et al. to inhibit growth of a human lymphoma xenografted into scid mice (17); it was unclear whether this reflected a direct effect of the drug on tumor cells or stimulation of host immune responses. Bai et al. reported that fenbendazole reduced the engraftment of brain tumors in nude mice (18). Chung et al. reported in a meeting presentation (19) that high doses of fenbendazole, albendazole and mebendazole inhibited the growth of paclitaxel-resistant tumors. Solid tumors develop regions of severe hypoxia very early in their development, at diameters of less than 1 mm (5, 6). As tumors grow, they concomitantly elicit the development of their vascular beds through angiogenesis, neovascularization, and co-option of vessels from normal tissues. However, tumor vascular beds lack the organization and regulation found in the vasculature supporting healthy normal tissues. The vessels are tortuous and irregular, and lack the musculature that normally regulates blood flow. Blind ends and shunting are common, and vessels frequently have microscopic and macroscopic holes that permit plasma or blood to leak into surrounding tissue. In addition, the growing tumors often invade or compress blood and lymphatic vessels, further compromising perfusion. As a result, solid tumors contain regions, where temporary interruptions in blood flow through individual vessels or persistent regional deficiencies in perfusion produce transient and chronic hypoxia. Because molecular oxygen is a potent chemical radiosensitizer (4–6, 20), hypoxic tumor cells are resistant to radiation, can survive radiation regimens that would eradicate fully aerobic cell populations, and can cause tumors to recur after radiation therapy. Intensive efforts in our laboratory and many others, have therefore been devoted to improving the outcome of radiation therapy by combining radiation with drugs that improve tumor oxygenation,
Orlistat is a medication that can help you lose weight or maintain weight loss by decreasing the amount of fat that your body absorbs from the food you eat. A healthcare provider will recommend a reduced-calorie diet when taking this medication. You can take this medication with a glass of water during meals.
Prescription orlistat is used in overweight people who may also have high blood pressure, diabetes, high cholesterol, or heart disease. Orlistat is also used after weight-loss to help people keep from gaining back that weight. Orlistat is in a class of medications called lipase inhibitors.
Orlistat (Xenical) is a drug that can help with weight loss. Research has shown that taking this medication along with eating a healthy diet and keeping active can help with losing weight.
Description. Ivermectin is used to treat river blindness (onchocerciasis), intestinal infection from threadworms (strongyloidiasis), and other kinds of worm infections. Ivermectin is an anthelmintic. It works by interfering with the nerve and muscle functions of worms, by paralyzing and killing them.
If you have a weak immune system (caused by disease or by using certain medicine), you may need to take more than one dose of ivermectin. Some people who have a weak immune system need to take this medicine on a regular basis. Follow your doctor's instructions
Ivermectin is neither a steroid nor an antibiotic; it is an antiparasitic medication. While effective in treating certain parasitic infections, its misuse can lead to adverse effects. Understanding its correct use is vital for health and safety.
Take this medication by mouth with a full glass of water (8 ounces or 240 milliliters) on an empty stomach (at least 1 hour before a meal). Take ivermectin as directed by your doctor, usually as a single dose or a series of doses. The dosage is based on your weight, medical condition, and response to treatment.
Minoxidil isused to stimulate hair growth and to slow balding. It is most effective for people under 40 years of age whose hair loss is recent. Minoxidil has no effect on receding hairlines. It does not cure baldness; most new hair is lost within a few months after the drug is stopped
Minoxidil works byincreasing blood flow to hair follicles and extending the growth phase of hair.It's believed to help by widening blood vessels and stimulating hair follicles, encouraging them to enter the growth phase.While the exact mechanism is still not fully understood, it's known to be a vasodilator and may also affect potassium channels in hair follicle cells.
The best times to apply Minoxidil are in themorning and evening. You should use it twice per day, about 12 hours apart. Many people apply it after showering or before bed when their hair is dry. Using it at set times each day helps make it a consistent routine.