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Antiepileptic Drugs

Our Complete range of products are and Levetiracetam.

Levetiracetam

  • CAS No. 102767-28-2
  • Groups Anti-epileptic
  • IUPAC ID (S)-2-(2-oxopyrrolidin-1-yl)butanamide
  • Molar mass 170.209 g/mol
  • Soluble in Water
  • Metabolism Enzymatic hydrolysis of acetamide group
  • Elimination half-life 6–8 hrs

Levetiracetam is an anticonvulsant medication used to treat epilepsy. Levetiracetam may selectively prevent hypersynchronization of epileptiform burst firing and propagation of seizure activity. Levetiracetam binds to the synaptic vesicle protein SV2A, which is thought to be involved in the regulation of vesicle exocytosis. Although the molecular significance of levetiracetam binding to synaptic vesicle protein SV2A is not understood, levetiracetam and related analogs showed a rank order of affinity for SV2A which correlated with the potency of their antiseizure activity in audiogenic seizure-prone mice.

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