Capecitabine is a prodrug which metabolizes in higher concentrations in tumour cells to the active drug 5-Fluorouracil (5-FU). This is because an enzyme, thymidine phosphorylase, required in the last step of conversion to 5-FU is present in higher concentrations in certain cancer cells of breast, colon and rectum. The upregulation of thymidine phosphorylase by docetaxel makes it a synergistic combination with capecitabine. Capecitabine provides a valuable option in patients of metastatic breast cancer who are resisitant to anthracycline and paclitaxel-containing regimens or those for whom anthracyclines are contraindicated.
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L/C, D/A, Western Union, ,
Packaging Details : Capecitabine
150 mg
IHS
Tablets
Strip
10
Capecitabine
500 mg
IHS
Tablets
Strip
10
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Bhanu Bhardwaj (gls pharma ltd)
R-4, Khirki Main Road, Malviya Nagar, Delhi - 110023
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