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Our Complete range of products are Tetrodotoxin Citrate Liquid and Liquid Tetrodotoxin Citrate Free.
Biological Activity for Tetrodotoxin citrate
\nTetrodotoxin citrate, the water-soluble citrate salt of tetrodotoxin, is a reversible, potent, selective and high affinity inhibitor of voltage gated sodium channels Nav 1.6, 1.1, 1.3, 1.4, 1.2 and 1.7 (IC50 values are 2.3 nM, 4.1 nM, 5.3 nM, 7.6 nM, 14 nM and 36 nM, respectively). Binding is reversible and high affinity (Kd = 1-10 nM). Tetrodotoxin shows antagonism of aconitine-induced cardiac toxicity, analgesic effects in mouse models of neuropathy and prolonged duration of local anesthesia in animals when combined with capsaicin. Tetrodotoxin also shows pH-dependent blockade of canine cardiac L-type Ca2+ (Cav1.x) channels, blocks primary reward in an animal study of drug-seeking lever pressing.
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Packaging Details : WELL PACKED AND STORED IN A SUITABLE CONTAINER
Delivery Time : 2-3 DAYS
It is a highly specific Na + channel blocker in excitable tissues. Purified from Fugu Fish organs (Takifugu oblongus). 10 -8 M block nervous system; 10 -5 M block heart muscle. The binding to Na + channel is reversible. ED 50 = 3.7 nM. Stable at room temperature, store preferably at 4°C
Additional Information:
Payment Terms : L/C, D/A, Western Union,
Packaging Details : WELL PACKED AND STORED AND SUITBLE CONTAINER
Delivery Time : 2-3 DAYS
Mr. Rahul (Heritage Chemical)
House No:D/45A, Silvassa, Dadra & Nagar Haveli - 396230, India
https://www.heritagechemical.co.in
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