2,2-dichloro-n-[(1 r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonyl phenyl)propan-2-yl]acetamide

we are offering 2,2-dichloro-n-[(1 r,2s)-3-fluoro-1-hydroxy-1-(4-methylsulfonyl phenyl)propan-2-yl]acetamide.
CAS: 73231-34-2
MF: C12H14Cl2FNO4S
MW: 358.21
mp 153 °C
storage temp. 0-6°C
form solid
Chemical Properties White Crystalline Powder
Usage Fluorinated derivative of thiamphenicol. Inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. An antibacterial
Usage Antibacterial;Protein synthesis inhibitor
Usage Florfenicol is a fluorinated derivative of thiamphenicol. Florfenicol inhibits bacterial protein synthesis by binding to ribosome 50S and 70S subunits. Florfenicol is used as an antibacterial.
Usage Florfenicol is synthesised from thiamphenicol by replacing the 3-hydroxy group with fluorine, first synthesised at Schering in 1980. By replacing the hydroxy group, it was rationalised that chloramphenicol resistance via chloramphenicol acetyltransferase could be eliminated. Florfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Florfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Florfenicol has been extensively studied with over 400 literature citations.
Antibiotics, and produce broad-spectrum antibacterial effect by inhibiting peptide transferase activity, broad antibacterial spectrum, including Gram-positive, Gram -negative bacteria
And Mycoplasma