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Contact SupplierAcid capped poly(D,L-lactide-co-glycolide) (PLGA-acid, PLGA-COOH, PLGA acid terminated, D,L-LA/GA=50:50) can be used to prepare nanoparticles, which can be further modified by amine-reactive entities. PLGA-COOH can be used to prepare polymer-drug conjugates.
Poly (lactic-co-glycolic acid) (PLGA) is one of the most effective biodegradable polymeric nanoparticles (NPs). It has been approved by the US FDA to use in drug delivery systems due to controlled and sustained- release properties, low toxicity, and bio compatibility with tissue and cells.