Acetone, Chemical Formula : CH3COCH3

CAS Number: 67-64-1, Molecular Weight: 58.08, Chemical Formula: CH3COCH3, EINECS EC Number: 200-662-2, FEMA: ----,

Acetone BP Ph Eur Grade Specifications
Ph Eur monograph
C3H6O --- 58.08 --- CAS 67-64-1

DEFINITION
Propanone.

CHARACTERS
Appearance: Volatile, clear, colourless liquid.
Solubility: Miscible with water and with ethanol (96 per cent). The vapour is flammable.

IDENTIFICATION
A. It complies with the test for relative density (see Tests).
B. To 1 ml, add 3 ml of dilute sodium hydroxide solution and 0.3 ml of a 25 g/l solution of sodium nitroprusside. An intense red colour is produced which becomes violet with the addition of 3.5 ml of acetic acid.
C. To 10 ml of a 0.1 per cent V/V solution of the substance to be examined in ethanol (50 per cent V/V), add 1 ml of a 10 g/l solution of nitrobenzaldehyde in ethanol (50 per cent V/V) and 0.5 ml of strong sodium hydroxide solution. Allow to stand for about 2 min and acidify with acetic acid. A greenish-blue colour is produced.

TESTS
Appearance of solution: To 10 ml add 10 ml of water. The solution is clear and colourless.
Acidity or alkalinity: To 5 ml add 5 ml of carbon dioxide-free water, 0.15 ml of PhPh solution and 0.5 ml of 0.01 M sodium hydroxide. The solution is pink. Add 0.7 ml of 0.01 M hydrochloric acid and 0.05 ml of methyl red solution. The solution is red or orange.
Relative density: 0.790 to 0.793.
Reducing substances: To 30 ml add 0.1 ml of 0.02 M potassium permanganate and allow to stand in the dark for 2 h. The mixture is not completely decolourised.
Related substances: Gas chromatography. To pass the test (0.05 per cent V/V).
Matter insoluble in water: Dilute 1.0 ml to 20 ml with water. The solution is clear.
Residue on evaporation: Maximum 50 ppm.
Water: Maximum 3 g/l, determined on 10.0 ml. Use 20 ml of anhydrous pyridine as solvent.

STORAGE
Protected from light.

IMPURITIES
Specified impurities A, B, C.
A. CH3-OH: methanol,
B. CH3-CHOH-CH3: propan-2-ol (isopropanol),
C. C6H6: benzene.