
Company Information
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Contact Supplier1. Basic identity
Name: Acetonitrile (systematic: ethanenitrile)
Typical abbreviations: MeCN, ACN
CAS No.: 75-05-8
Molecular formula: C₂H₃N
Molecular weight: 41.05 g·mol⁻¹
2. Key physical properties (typical)
Appearance: Colorless liquid
Odour: Mild, ethereal/ether-like
Boiling point (≈): 81.6 °C
Melting point (≈): −45.7 °C
Density (20 °C, ≈): 0.786 g·cm⁻³
Refractive index (n₂₀D): ≈ 1.344
Viscosity (25 °C, ≈): ≈ 0.3–0.4 cP
Dielectric constant (20 °C): ≈ 36.6 (polar aprotic solvent)
Solubility: Completely miscible with water and most organic solvents
Flammability: Flammable liquid / vapour (low flash point) — handle as combustible chemical
3. Major applications
HPLC / Chromatography mobile phase (very common).
Synthetic organic solvent — SN2, nitrile chemistry, coupling reactions, organometallic chemistry.
Electrolytes / battery industry (component for Li-ion electrolytes).
Pharmaceuticals & fine chemicals synthesis and extractions.
Polymer chemistry (polymerizations, polymer processing solvents).
Spectroscopy & analytical labs (NMR solvent sometimes — deuterated form CD₃CN used for NMR).
Industrial processes — cyanohydrin production, acetamide/other derivatives, extraction/cleaning tasks where polar aprotic solvent is required.
4. Safety, hazards & first aid (practical summary)
Hazards: Flammable; harmful by inhalation, ingestion and skin contact; can affect the central nervous system (headache, dizziness, nausea); chronic exposure potential (see MSDS).
PPE: Safety goggles, chemical-resistant gloves (nitrile gloves okay), lab coat/coveralls, use in well-ventilated area or fume hood; respirator if ventilation inadequate.
Storage: Tightly closed containers, cool/ventilated area, away from heat/ignition sources and strong oxidizers. Store per local/regional regulations.
Spill response: Eliminate sources of ignition; absorb spills with inert material (e.g., vermiculite), collect for proper disposal; prevent discharge to drains.
Fire-fighting: Use foam, dry chemical or CO₂ — do not use water jet. Firefighters should wear SCBA.
First aid:
Inhalation: Move to fresh air; seek medical attention if symptoms persist.
Skin contact: Remove contaminated clothing; wash skin with soap/water.
Eye contact: Rinse cautiously with water for several minutes; seek medical attention.
Ingestion: Do NOT induce vomiting — seek immediate medical help.
Always use the supplier’s MSDS/SDS for complete and authoritative safety instructions and emergency data.