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Azacitidine injection is used to treat patients with French-American-British (FAB) myelodysplastic syndrome (bone marrow problem) subtypes, including refractory anemia or chronic leukemia. This medicine is also used to treat juvenile myelomonocytic leukemia (JMML). In addition to their differentiation-inducing activity, these agents also have direct cytotoxic effects. In a number of phase 2 trials 5-azacitidine and decitabine given to patients with MDS resulted in an overall response rate of
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