C-Terminal Sequencing Service

Protein integrity is a crucial charateristics for protein, as protein truncation or microheterogeneity can lead to malfunction of protein. It is even more critical for the quality tests of biopharmaceutical products, such as antibodies and vaccines. Thus, analysis of the C-terminal sequence of protein products is necessary for evaluating the quality and function of protein products. MtoZ Biolabs have developed a LC-MS/MS system, which is suitable for analyzing both N-terminal sequence and C-terminal amino acid sequence and PTMs. We strictly follow the ICH Q6B Guidance to fulfill our customers’ needs.MtoZ Biolabs provides integrate C-Terminal Sequencing Service.

Analysis Workflow

Applications

Determination of N/C-Terminal Sequence of Proteins/Peptides/Antibodies/Vaccines|Analysis of PTMs

Sample Submission RequirementsDeliverables

Experimental Procedures|Parameters of Liquid Chromatography and Mass Spectrometer|MS Analysis Raw Data Files|N/C-Terminal Amino Acid Sequences

Related Services

Protein Sequencing

Protein De Novo Seq

N-Terminal Sequencing

C-Terminal Sequencing

Edman Degradation

Protein Full-Length Sequencing

Protein Analysis

Protein Identification

Protein Mass Measurement

PTMs Identification

PTM Analysis

Phospho Proteomics

Acetyl Proteomics

Ubiquitin Proteomics

Glyco Proteomics

Disulfide Bond

Histone Modifications