Calcium Dobesilate

Calcium dobesilate is a drug used to reduce hemorrhage in diabetic retinopathy. Calcium dobesilate is a vasoactive drug with presumed effects on endothelial integrity, capillary permeability and blood viscosity. It is often recommended for venous disorders, and also prescribed for diabetic retinopathy and other microvascular disorders.
Calcium dobesilate has a comprehensive mode of action. It increases endothelial nitric oxide levels by enhancing the activity of nitric oxide synthase and decreasing capillary hyperpermeability.calcium dobesilate shows anti-platelet and fibrinolytic activities by inhibiting platelet activation factor (paf) and enhancing the release of tissue plasminogen activator (tpa), thereby improving the local blood flow to tissues, otherwise inhibited due to thrombosis. Calcium dobesilate also inhibits the two pathophysiological reactions in diabetes, viz. Polyol pathway and glycation of proteins, due to its inhibitory effects on aldose reductase.
Synonyms: calcium; 2, 5-dihydroxybenzenesulfonate
cas number: 20123-80-2, mol. Formula: 2c6h5o5s.ca, mol.weight: 418.41
calcium dobesilate is a white powder. It is soluble in water with melting point of 251°c.
Standard: offered of pharmaceutical grade bpuspep
packing: offered in export worthy packing of 25 kilos or as per our customer requirements