Camptothecin

Camptothecin
cas no.: 7689-03-4
specification: 98%,99%
ingredient:camptotehcin
test method: hplc
appearance: brown crystalline powder; easy to loss activity under light.
Botanical source: camptotheca acuminata decne’s fruit and leaf
molecular formula: c20h16n2o4
molecular weight: 348.36
action and uses:
camptothecin affects the activity of the enzyme topoisomerase i, whose normal action is to cleave, unwind, and religate dna. When camptothecin binds to topoisomerase i, it will be able to cleave but not to religate dna. Thereby, camptothecin causes single strand breaks in dna
camptothecin is a plant secondary metabolite used as an anti-cancer drug that damages dna, leading to the destruction of the cell.it comes from camptotheca acuminata, a deciduous tree found in southern china. A close analogue, 9-methoxycamptothecin, is also present in the same source.
package: 25 kg/ fiberboard drum,inner with plastic bag.
Storage: store in cool & dry area, keep away from the direct light and heat.
Shelf life: two years if properly stored