Chloramphenicol Capsule for Meningitis, Rickettsial Infections

Chloramphenicol is an antibiotic that prevents the accumulation of bacterial proteins in the body. It was discovered in 1948, Chloramphenicol was administered to treat a variety of pathogens, including gram-positive and gram-negative bacteria, and severe infections caused by bacterial growth. One of the factors contributing to Chloramphenicol’s increased therapeutic potential is its lipid solubility. This characteristic allows it to easily diffuse through bacterial cell membranes, and attaches to the 50s subunit of the bacterial ribosome, thereby obstructing protein synthesis and inhibiting bacterial growth. Chloramphenicol capsule stops protein synthesis, leading to bacterial death and preventing proliferation. Let’s not forget, this drug also has some risks along with its benefits. For a breastfeeding mother or a woman planning to conceive while taking Chloramphenicol, it is strongly advised to consult a doctor beforehand. What is Chloramphenicol capsule prescribed for? Chloramphenicol, an antibiotic, can be used in conditions where other antibiotics may not be effective. The capsule works by inhibiting the growth of bacterial proteins, thereby reducing the negative effects of the infection. They are prescribed for: Typhoid fever Meningitis Rickettsial infections Conjunctivitis (as Chloramphenicol eye drops) Serious infections caused by Haemophilus influenzae, Streptococcus pneumoniae, Neisseria meningitidis, and others What are the side effects of Chloramphenicol capsule? Side effects of Chloramphenicol capsule can vary, depending on the patient’s conditions. It is closely associated with severe conditions like aplastic anemia, and patients with jaundice have experienced liver injuries. Nausea and vomiting Diarrhoea Inflammation of the optic nerve Weakness and numbness in your hands and feet Rash More serious side effects include: Bone marrow suppression: which can lead to aplastic anaemia, a potentially life-threatening condition. Gray baby syndrome.