Dabigatran, Grade : Medicine, Form : Oral Pellet Capsule

Niksan Pharmaceutical is leading manufacturer and distributer of the Dabigatran among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Dabigatran API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Dabigatran in the domestic level as well as the international market. 

Niksan Pharmaceutical provides Dabigatran API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Dabigatran API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Dabigatran is one type of anticoagulant medications which is used to preventing blood clots from forming in the body.

SYNONYMS: Dabigatran

IUPAC NAME:3-[1-(2-{[(4-carbamimidoylphenyl)amino]methyl}-1-methyl-1H-1,3-benzodiazol-5-yl)-N-(pyridin-2-yl)formamido]propanoic acid

CAS NO: 211914-51-1

FORMULA: C₂₅H₂₅N₇O₃

MOLECULAR MASS: 627.734 g/mol

STORAGE OF DABIGATRAN:Store PRADAXA at room temperature between 68° F to 77° F (20° C to 25° C). After opening the bottle, use PRADAXA Capsules within 4 months. Safely throw away any unused PRADAXA Capsules after 4 months. Keep PRADAXA Capsules in the original bottle or blister package to keep it dry (protect the capsules from moisture).

APPLICATIONS OF DABIGATRAN: Dabigatran is used to treat deep vein thrombosis (DVT; a blood clot, usually in the leg) and pulmonary embolism (PE; a blood clot in the lung) in adults and children 3 months of age and older who have been treated with an injectable anticoagulant ('blood thinner').

HOW TO USE: You can take dabigatran with or without food, but try to take it at the same time every day. Swallow the capsules whole with a drink of water. Do not open dabigatran capsules before taking them as this increases the risk of side effects. If you have trouble swallowing pills, speak to your doctor or pharmacist.

HOW DABIGATRAN WORKS: Dabigatran is in a class of anticoagulant medications called direct thrombin inhibitors. It works by preventing blood clots from forming in the body.

CONTRAINDICATIONS OF DABIGATRAN: Dabigatran is contraindicated in patients with a history of serious dabigatran hypersensitivity, such as an anaphylactic reaction. Dabigatran is contraindicated in any patient with active pathological bleeding, as dabigatran use increases the risk of bleeding and can cause significant, sometimes fatal bleeding.

PHARMACOKINETICS OF DABIGATRAN: Dabigatran pharmacokinetics are dose proportional after single doses of 10 to 400 mg. Given twice daily, dabigatran's accumulation factor is approximately two. Elimination Dabigatran is eliminated primarily in the urine. Renal clearance of dabigatran is 80% of total clearance after intravenous administration.

SIDE EFFECTS OF DABIGATRAN:   if you have any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, headache, dizziness, or weakness, pain, swelling, or discomfort in a joint, Stomach pain or indigestion, pinpoint red spots on your skin, unusual nosebleeds, or unusual vaginal bleeding that is heavier than normal.