Sl Samarth Dopamine Hcl Injection, Medicine Type : Allopathic

Product Name: Dopamine HCL Injection
Brand Name: Dopar
strength: 200 mg/ 2ml
Packing: 25 Ampoules Per Box

• Drug Class: Dopaminergic Agent, Inotropic Agent
• Purpose: Used to increase blood pressure and cardiac output in conditions such as shock, heart failure, and low blood pressure due to various causes.
• Administration: Administered intravenously.
• Mechanism of Action:
  • Stimulates dopamine receptors in the body, leading to increased heart rate and contractility, vasodilation in renal and splanchnic circulations, and vasoconstriction in peripheral blood vessels.
  • Different dosages produce different effects: low doses primarily affect renal and splanchnic vasodilation, intermediate doses increase cardiac output, and high doses result in vasoconstriction.
• Indications:
  • Used in the management of shock (e.g., septic shock, cardiogenic shock).
  • Employed as a vasopressor in patients with hypotension.
• Dosage:
  • Dosage varies based on the indication, patient's hemodynamic status, and individual response to treatment.
  • Typically administered as a continuous infusion.
• Precautions:
  • Monitor closely for extravasation as it can cause tissue necrosis.
  • Use with caution in patients with arrhythmias, hypertension, or peripheral vascular disease.
• Contraindications:
  • Hypersensitivity to dopamine or any components of the formulation.
  • Pheochromocytoma (a rare tumor of adrenal gland tissue).
• Adverse Effects:
  • Common adverse effects include tachycardia, arrhythmias, hypertension, headache, and nausea.
  • Extravasation can lead to tissue necrosis.
• Special Populations:
  • Use with caution in elderly patients and those with pre-existing cardiovascular conditions.
  • May exacerbate underlying arrhythmias or ischemic heart disease.
• Storage:
  • Store at controlled room temperature.
  • Protect from light.
• Drug Interactions:
  • Concurrent use with monoamine oxidase inhibitors (MAOIs) or tricyclic antidepressants may increase the risk of hypertensive crisis.
  • Beta-blockers may attenuate the effects of dopamine.
• Monitoring:
  • Continuous monitoring of blood pressure, heart rate, and ECG during administration.
  • Regular assessment of urine output and renal function.
• Patient Counseling:
  • Inform patients about the purpose of the medication and potential side effects.
  • Instruct patients to report any adverse reactions or changes in symptoms promptly.