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Contact SupplierWe are offering fosfomycin sodium
synonyms: phosphomycin disodium salt
cas: 26016-99-9
einecs: 247-409-2
assay: 99% min.
standard: ep/bp/usp
packing: 25kg/cardboard drum
character: room temperature a white crystalline powder, hygroscopic, easily soluble in water, dissolution heat.
usage: disodium phosphonomycin is a broad-spectrum antibiotics, mainly used for chickens, ducks, pigs, staphylococcus, streptococcus, e. Coli, salmonella and other gram-negative bacteria cause acute and chronic intestinal diseases.
for the treatment of intestinal infection, with β-lactams, aminoglycosides in combination.
for the treatment of respiratory and lung infections, with macrolides, β-lactam combination.
for staphylococcus aureus infection cure, should be with erythromycin, rifampin combination.
for the treatment of severe respiratory tract infections, sepsis, peritonitis, etc. To increase the dose. Need and β-lactam or aminoglycoside combination.
1. Antibacterial spectrum, bioavailability, faster absorption, antimicrobial and strong, not diet affected. Against gram-positive bacteria, negative bacteria have a role in the killing, especially pseudomonas aeruginosa, proteus, salmonella, and a variety of pharmaceutical resistant staphylococcus aureus and e. Coli are able to show excellent antibacterial activity. For animals, there is no resistance and cross-resistance, good clinical outcomes.
2. Bactericidal quickly: this is a fast fungicides, and its role in the 1-2 hours later is already evident. About 25% of e. Coli in contact with fosfomycin (12.5μg/ml) was 1 hour after the killing, and all died within 4-6 hours. Pseudomonas aeruginosa and staphylococcus aureus were also at 4 and 8 hours were all killed.
3. Low toxicity, irritation on the body, does not have acute toxicity and adverse reactions, without increasing the burden on the kidneys.
4. Residue: in the muscles and organs to achieve the elimination of residual standard time is 48-72 hours.