Fosinopril Sodium

We are offering fosinopril sodium.
Fosinopril sodium is a phosphinic acid-containing angiotensin-converting enzyme inhibitor that is effective in the treatment of hypertension. It is a prodrug that is converted to its active metabolite fosinoprilat.
Fosinopril sodium is the sodium salt of fosinopril, a phosphinic acid-containing angiotensin-converting enzyme (ace) inhibitor with antihyper- tensive activity. Fosinopril sodium is an ester prodrug that is hydrolysed by esterases to its active metabolite fosinoprilat. Fosinoprilat specifically and competitively inhibits angiotensin-converting enzyme thereby decreasing the formation of the potent vasoconstrictor angiotensin ii, resulting in diminished vasopressor activity. In addition, angiotensin ii-mediated aldosterone secretion by adrenal cortex is decreased, which results in a decrease of sodium retention and an increase of serum potassium.

synonyms: sodium; (2s, 4s)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxy propoxy)-(4-phenylbutyl) phosphoryl] acetyl] pyrrolidine-2-carboxylate
cas number: 88889-14-9, mol. Formula: c30h46nnao7p, mol.weight: 586.65
fosinopril sodium is white to off-white crystalline solid. It is soluble in water (117 mgml at 25 °c), dmso (