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It inhabits the intracellular phosphorylation of numerous tyrosine kinases associated with transmembrane cell surface receptors, including the tyrosine kinase associated with the epidermal growth factor receptor(EGFR-TK), EGFR is expressed on the cell surface of many normal cell and cancer cells.

Indication : It is indicated as monotherapy for the continued treatment of patients with locally advanced metastatic non-small cell lung cancer after failure of both platinum.