Glimepiride, Purity : 97-98%

Niksan Pharmaceutical and our group companies Niksan healthcare are the one of largest manufacturer and supplier of Glimepiride formulations and Glimepiride API in Ankleshwar, Gujarat, India. We are sullying the best quality of Glimepiride API all around the India as well as in the whole world. Our product Glimepiride praised by our clients and also by the other companies.

Niksan Pharmaceutical is the world leading manufacturing and supplying company of the Glimepiride products and API.

Thus we are Indian based company we supplying our best quality products to every states of India for many years like Jammu andKashmir, Kerala, Punjab, Rajasthan, Andhra Pradesh, Haryana, Telangana, Bihar, Karnataka,Delhi, Tamil Nadu, Odisha, Maharashtra, West Bengal, Uttar Pradesh, Gujarat, Madhya Pradesh, Himachal Pradesh, Goa, Chhattisgarh etc.

Niksan Pharmaceutical also exports huge quantity of best quality Glimepiride API products to the other nations like Puerto Rico, Indonesia, Nepal, Ghana, United States, Philippines, Jordan, Pakistan, Nigeria, Sri Lanka, United Arab Emirates, South Africa, Bangladesh, Netherlands, Taiwan, Iraq, Saudi Arabia, Venezuela, Hong Kong, Singapore, Vietnam, Egypt, South Korea, Algeria, Morocco, France, Israel, Australia, United Kingdom, Canada, Malaysia, Italy, Thailand, Colombia, Mexico, Argentina, Spain, Germany, Brazil, Japan and many south eastern countries.

Glimepiride is the type of drug which is used in the treatment of the type II diabetes mellitus. Glimepiride is basically the oral dosage form. With the diet and proper exercise and treatment of Glimepiride works more effectively.Glimepiride patented in year 1979 and then it is approved for the medical use in the year 1995.

Glimepiride come in the sulfonylurea class of drug which acts by increasing the body insulin which cause decrease in blood sugar.

SYNONYMS OF GLIMEPIRIDE:  Glimepirida, Glimépiride, Glimepiride, Glimepiridum.

IUPACNAME: 3-Ethyl-4-methyl-N-[2-(4-{[(trans-4-methylcyclohexyl) carbonyl] sulfonyl} phenyl) ethyl]-2-oxo-2, 5-dihydro-1H-pyrrole-1-

Carboxamide

CAS NO: 93479-97-1

FORMULA: C24H34N4O5S

MOLECULAR MASS: 490.62 g/mol

HOW TO USE: Read the leaflet of the Glimepiride. the medicine is only taken one time a day so take the medicine in morning orally with breakfast.to take the most benefit of Glimepiride take it regularly at a same time for days. If you are already taking other diabetic medicines take your doctors advice to how to use the Glimepiride medication.

HOW GLIMEPIRIDE WORKS: Glimepiride main work is to reduce the blood sugar level by stimulating the insulin from pancreatic beta cells. By this process the peripheral glucose uptake and by this the blood sugar level decreased by the Glimepiride.

CONTRAINDICATIONS OF GLIMEPIRIDE: If you have any allergy, tell your doctor before taking these medicinesand other inactive ingredients which can cause allergic reactions. Because of the  action of the drug the blood sugar level will decrease by this the blurred vision and drowsiness effects are seen so do not take this medicine while driving or doing any machinery works which can cause hazardous reaction. Do not go out in sun because this medicine can make you sensitive to the sun.

PHARMACOKINETICS OF GLIMEPIRIDE: Glimepiride is taken orally and will easily absorb after the administration in 1 hour and reach the blood peak plasma concentration within 3 hours. The plasma protein binding of Glimepiride is more than 99.5%. The drug will metabolise completely in liver. Basically the half-life of Glimepiride is 5-8 hours but it can increase by taking multiple dosages. The excretion of Glimepiride is mainly (60%) done by urinationand the other is done in feces.