Hepbest Tablets, Composition : Tenofovir Alafenamide (25mg)

Hepbest tablets contain the active ingredient Tenofovir Alafenamide (TAF), an antiviral medication.It is primarily used to treat chronic hepatitis B virus (HBV) infection in adults and adolescents.

 

 

Key Characteristics:

 

• Mechanism of Action: Hepbest works by preventing the replication of the hepatitis B virus.TAF is a prodrug, meaning it is converted into the active form, tenofovir, inside the body's cells, specifically in the liver where the virus resides.Tenofovir then interferes with the viral reverse transcriptase enzyme, which is essential for the virus to multiply.By blocking this process, the drug reduces the amount of HBV in the body and helps to improve liver health, lowering the risk of complications like liver failure or liver cancer.

   
   
   
   

   

• Targeted Therapy: TAF is an advanced form of tenofovir that delivers a higher concentration of the active drug to the liver with a lower dose, which helps reduce the risk of certain side effects (like kidney and bone issues) that were associated with older forms of the drug.

• Uses:

  • Chronic Hepatitis B (HBV) infection: This is the main use for Hepbest.It is prescribed for long-term management of the infection.

     
     

     

  • HIV-1 infection: In some cases, it may be used as part of a combination therapy with other antiretroviral drugs to treat HIV-1 infection, particularly in patients who are co-infected with both HBV and HIV.

     

     

 

Dosage and Administration:

 

• Hepbest is taken orally, typically once a day, with food.Taking it with food increases the absorption of the medicine into the body.

   
   

   

• It is crucial to take the medication exactly as prescribed by a healthcare professional and not to miss any doses.Stopping the medication abruptly can lead to a flare-up of the hepatitis B infection.

   
   

   

 

Side Effects:

 

While generally well-tolerated, Hepbest can cause side effects, which are usually mild. The most common ones include:

 

• Headache

   

   

• Nausea and vomiting

   

   

• Diarrhea

   

   

• Fatigue or weakness

   

   

• Abdominal pain

   

   

• Dizziness

   

   

Less common but more serious side effects can occur, and patients should contact their doctor immediately if they experience symptoms of:

• Lactic acidosis: This is a rare but serious condition characterized by a buildup of lactic acid in the blood. Symptoms include unusual weakness, muscle pain, and rapid breathing.

• Severe liver problems: Signs can include yellowing of the skin or eyes (jaundice), dark urine, or light-colored stools.

   

   

• Kidney problems: The drug may cause kidney damage in some cases, so regular monitoring of kidney function is often necessary.

   

   

 

Important Considerations:

 

 

• Hepbest is a prescription-only medication and should only be taken under the guidance of a physician specializing in chronic hepatitis B.

   

   

• Patients should be tested for HIV before starting Hepbest. If they are co-infected with HIV, the drug must be taken with other antiretroviral agents as part of a complete regimen.

   

   

• The medication does not prevent the transmission of HBV to others.Patients should continue to practice safe habits to prevent the spread of the virus.

   
   

   

• Regular blood tests are required during treatment to monitor liver function, the level of the virus, and other health markers.