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Contact SupplierIbuprofen is a widely used over-the-counter (OTC) and prescription-strength medication that belongs to a class of drugs called nonsteroidal anti-inflammatory drugs (NSAIDs).
Description and Form
Ibuprofen is a white crystalline powder that is practically insoluble in water. Ibuprofen tablets are typically round, and may be coated for easier swallowing. They are available in various strengths, most commonly 200 mg for over-the-counter use, and higher strengths like 400 mg, 600 mg, or 800 mg for prescription use.
Mechanism of Action
Ibuprofen works by inhibiting the production of prostaglandins, which are hormone-like substances in the body that cause inflammation, pain, and fever.It does this by blocking the enzymes cyclooxygenase (COX-1 and COX-2) which are responsible for creating prostaglandins. By reducing the level of prostaglandins, ibuprofen helps to alleviate these symptoms.
Uses
Ibuprofen tablets are used to treat a wide range of conditions, including:
Pain Relief: Mild to moderate pain from various causes, such as headaches, muscle aches, backaches, dental pain, and menstrual cramps.
Inflammation: Reducing inflammation and swelling associated with conditions like arthritis (rheumatoid arthritis and osteoarthritis), sprains, and strains.
Fever Reduction: Lowering a high body temperature (fever) associated with the common cold or flu.
Dosage and Administration
The dosage of ibuprofen varies depending on the condition being treated, the patient's age and weight, and whether it's an OTC or prescription product.
Over-the-counter (OTC) use: For adults, a common dose is 200 to 400 mg every 4 to 6 hours as needed. The maximum daily dose for OTC use is typically 1200 mg.
Prescription use: A doctor may prescribe higher doses, generally up to 3200 mg per day, divided into multiple doses.
It is recommended to take ibuprofen with food or milk to reduce the risk of stomach upset. Always follow the directions on the label or as prescribed by your doctor, and do not exceed the recommended dose.
Side Effects and Risks
While generally safe when used as directed, ibuprofen can cause side effects. Common side effects include:
Nausea
Upset stomach or indigestion
Diarrhea or constipation
Dizziness or headache
More serious, though less common, side effects can occur, particularly with long-term use or at high doses. These include:
Gastrointestinal issues: Stomach ulcers, bleeding, or perforation of the stomach or intestines.
Cardiovascular risks: An increased risk of heart attack or stroke, especially in people with pre-existing heart disease.
Kidney problems: Impaired kidney function.
Allergic reactions: Hives, swelling, or difficulty breathing.
Serious skin reactions: Skin rashes with blistering and peeling.
It is crucial to talk to a healthcare professional before taking ibuprofen if you have a history of heart disease, stomach ulcers, kidney or liver disease, high blood pressure, or if you are pregnant.You should also be aware that ibuprofen can interact with other medications, such as blood thinners and certain antidepressants.


