Lamotrigine

Lamotrigine is an anti-epileptic agent and mood stabilizer. The physiologic effect of lamotrigine is by means of decreased central nervous system disorganized electrical activity. Lamotrigine is a synthetic phenyltriazine with antiepileptic and analgesic properties. Lamotrigine enhances the action of gamma-aminobutyric acid, an inhibitory neurotransmitter, which may result in a reduction of pain-related transmission of signals along nerve fibers. This agent may also inhibit voltage-gated sodium channels, suppress glutamate release, and inhibit serotonin reuptake.