Loperamide, Formula : C₂₉h₃₃cln₂o₂·HCL

NIiksan Pharmaceutical is the world’s leading pharmaceutical company in the field of manufacturing, supplying and exporting of Loperamide and API. Niksan pharmaceutical provides wide range of API and Finished pharmaceutical products of Loperamide to the Niksan group companies and also to our customers in very affordable price.

Niksan Pharmaceutical are the manufacturer, supplier and exporter of the Loperamide in domestic and as well as worldwide.

Niksan Pharmaceutical are manufacturing and supplying Loperamide in the all over the Indians states like Punjab, Tamilnadu, Gujarat, Delhi, Uttar Pradesh, Bihar, Rajasthan, Maharashtra, west Bengal, Assam, Odisha.

Niksan Pharmaceutical manufacture and exports large quantity of Loperamide among the other nations from many years like Zimbabwe, Philippines, Tanzania, Singapore, Cambodia, Nepal, Ghana, Latvia, New Zealand, Kenya, Nigeria, South Africa, Netherlands, Puerto Rico, Indonesia, United Kingdom, France, United States, Canada, Moldova, Vietnam, Malaysia, Iraq, Sri Lanka, United Arab Emirates , Hong Kong, Jordan, Belgium, Australia, Ireland, Italy, Algeria, Pakistan, Thailand, Bangladesh, Taiwan, Saudi Arabia, Morocco, Israel , South Korea, Switzerland, Egypt, Iran, Romania , Sweden, Peru, Greece, Mexico, Spain , Colombia, Germany, Turkey, Poland, Japan, Brazil and many other countries.

Loperamide comes in the medicine class called antidiarrheal agents. Loperamide used in the treatment of diarrhoea and also use to control the frequency of diarrhoea. Loperamide is also used in the inflammatory bowel disease and short bowl syndromes.

SYNONYMS: Loperamid, Loperamida, Lopéramide, Loperamide, Loperamidum.

IUPAC NAME: 4-[4-(4-Chlorophenyl)-4-hydroxypiperidin-1-yl]-N, N-dimethyl-2,2-diphenylbutanamide

CAS NO: 53179-11-6

FORMULA: C₂₉H₃₃ClN₂O₂

MOLECULAR MASS: 477.04 g/mol (513.51 with HCl) g·mol

STORAGE CONDITION: Store medication at room temperature in dry place. Put it away from light and excessive heat. Do not put medication in bathroom or in kitchen. Keep it away from the range of children and pet.

HOW TO USE LOPERAMIDE: Take the medicine by mouth after the each loose stool. The dosage form might be different in children and adult. Do not take more than 8 mg dose in 24 hours. If you are taking the chewing tablet of Loperamide take it in empty stomach. Ask for your doctor’s advice if needed.

HOW LOPERAMIDE WORKS: Loperamide decrease the flow of liquid and electrolyte to the bowel, by doing this the bowel movement becomes slow by this the bowel movement will be decrease.

PHARMACOKINETIKCS OF LOPERAMIDE: Loperamide plasma concentrations will reach highest in 5hrs after taking the capsules and administration of liquid make it fast in approx. 2.5 hrs. The half-life of Loperamide is average 9.5-11.5 hrs. Loperamide binds with approximately 97% of plasma. The excretion of Loperamide is mostly done by feces.

SIDE EFFECTS OF LOPERAMIDE: The common side effects like dizziness, drowsiness, weakness. If taken in more quantity it can cause constipation also. Stop taking medicine if you see some side effects like nausea, vomiting, stomach pain, constipation, fast irregular heartbeats. The allergic reaction of this drug is rare but if you find effects like rash/itching, irritation tell your doctor about it.

PRECAUTIONS OF LOPERAMIDE: If you are taking the rapidly dissolving tablets keep your hand dry before taking medicine out of packet. Place tablet in mouth wait for it to dissolve and the swallow it with saliva. Stop taking medicine if you see some side effects like nausea, vomiting, stomach pain, constipation, fast irregular heartbeats. Tell your doctor if you have any allergic reaction with Loperamide.

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