Lornoxicam, Grade : Pharma Grade, CAS No. : 70374-39-9

Niksan Pharmaceutical is leading manufacturer and distributer of theLornoxicam among the other countries. Niksan Pharmaceutical is one of the major the supplier, distributer, exporter and manufacturer of the Lornoxicam API and finished formulations in Ankleshwar, Gujarat, India. The products of Niksan Pharmaceutical and Niksan group companies are widely appreciated by the clients and other companies.

Niksan Pharmaceutical is the supplier, manufacturer, exporter and trader of Lornoxicam in the domestic level as well as the international market. 

Niksan Pharmaceutical provides Lornoxicam API in all over Indian states like Jammu & Kashmir, Himachal Pradesh, Uttarakhand, Punjab, Kerala, Chandigarh, Chhattisgarh, Andhra Pradesh, Rajasthan, Meghalaya, Mizoram, Nagaland, Orissa, Pondicherry, Dadra and Nagar Haveli, Goa, Gujarat, Jharkhand, West Bengal, Karnataka, Kerala, Madhya Pradesh etc.

Niksan Pharmaceutical also provides Lornoxicam API and finished formulations in all other countries of the world like Germany, Switzerland, Poland, Latvia, Egypt, Lithuania, Estonia, Ukraine, Moldova, Russia, United States, Austria, Belarus, Serbia, India, Spain, Slovenia, Nigeria, Croatia, South Africa, Kazakhstan, Italy, Romania, Bulgaria, Portugal, South Korea, Greece, Philippines, Belgium, Saudi Arabia, Turkey, Japan etc.

Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties.

SYNONYMS: Chlortenoxicam, Lornoxicam, Lornoxicamum

IUPAC NAME: 6-chloro-4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1λ⁶-thieno[2,3-e][1,2]thiazine-3-carboxamide

CAS NO: 70374-39-9

FORMULA: C₁₃H₁₀ClN₃O₄S₂

MOLECULAR MASS:371.81 g/mol

STORAGE OF LORNOXICAM:No special storage conditions are required.

APPLICATIONS OF LORNOXICAM:LORNOXICAM is used to reduce and relieve pain and inflammation (swelling) in osteoarthritis and rheumatoid arthritis. LORNOXICAM works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins.

HOW TO USE: It should be taken with food or milk to avoid getting an upset stomach. It can cause serious complications like stomach bleeding and kidney problems if taken for a long time. Lornoxicam can raise your risk of blood clots, heart attack, or a stroke.

HOW LORNOXICAM WORKS: LORNOXICAM is used to reduce and relieve pain and inflammation (swelling) in osteoarthritis and rheumatoid arthritis. LORNOXICAM works by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzyme that makes other chemical prostaglandins.

CONTRAINDICATIONS OF LORNOXICAM: The drug is contraindicated in patients who must not take other NSAIDs, possible reasons including salicylate sensitivity, gastrointestinal bleeding and bleeding disorders, and severe impairment of heart, liver or kidney function.

PHARMACOKINETICS OFLORNOXICAM: Lornoxicam is eliminated following biotransformation to 5'-hydroxy-lornoxicam, which does not undergo enterohepatic recirculation. Glucoroconjugated metabolites are excreted in urine and faeces with a half-life of about 11 hours. Lornoxicam and its metabolites bind extensively to plasma albumin.

SIDE EFFECTS OF LORNOXICAM:  Allergic reaction like fever, chills, rash, hives, breathing difficulty, swelling over your face, lips, throat, running/stuffy nose and sneezing, Swelling (inflammation) of the intestine, Diarrhea, nausea, vomiting and indigestion, Blood disorders, Vision trouble, sensitivity to light.

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