Mannitol

Mannitol
Synonyms: DL-Mannitol; Hexahydroxyhexane
CAS: 69-65-8
EINECS: 200-711-8
Assay: 99% min.
Standard: BPEPUSP
Packing: 25kgcardboard drum
Character: Colorless to white needle-like or rhombic columnar crystals or crystalline powder. Odorless, has a cool sweet taste. Sweetness of sucrose about 57% to 72%. 8.37J per g of heat generated is about half glucose.
Containing a small amount of sorbitol. The relative density of 1.49. Specific rotation [α] D20-0.40 ° (10% aqueous solution). Minimal moisture absorption. Solution stability. Of acid, dilute alkali stable. Oxidation by oxygen in air does not. Soluble in water (5.6g100ml, 20 ℃) ​​and glycerol (5.5g100m1). Slightly soluble in ethanol (1.2g100m1). Soluble in hot ethanol. Almost insoluble in most other common organic solvents. 20% aqueous solution of pH 5.5 to 6.5.
Usage: Mannitol in medicine is a good diuretic to reduce intracranial pressure, intraocular pressure and renal pharmaceuticals, dehydration, sugar substitutes, also used as tablet excipients and solid, liquid diluent. Mannitol injection as a high penetration of antihypertensive pharmaceuticals, the clinical brain disorders, especially rescue the rescue of a pharmaceutical commonly used, to reduce intracranial pressure with antihypertensive pharmaceuticals require rapid, effective and accurate.
Used as a tablet excipient, mannitol no moisture absorption, fast drying, good chemical stability, but also has tasty, and good granulation Characters for anti-cancer pharmaceuticals, antibiotics, antihistamines, and vitamins and other large part of the tablet. In addition, pharmaceuticals used to sober up, mouth refreshing agent Chewable agent
Food additive, low-calorie sweetener; gum and candy anti-stick; nutritional supplement agents and tissue conditioner; moisturizer; filler.