Metformin 1000 Mg + Glimipiride Tablets For Clinical, Hospital

Novimet G1/G2 Forte Tablets

**Metformin 1000 mg + Glimepiride Tablets** are a combination of two antidiabetic medications used to manage type 2 diabetes mellitus. These tablets help control blood sugar levels in patients who cannot achieve adequate glycemic control through diet and exercise alone.

### Active Ingredients:

1. **Metformin (1000 mg)**: Belongs to the class of biguanides, which works by:

   - Reducing glucose production in the liver.

   - Increasing the body's sensitivity to insulin.

   - Improving the uptake and utilization of glucose by muscles.

2. **Glimepiride**: A sulfonylurea that:

   - Stimulates the pancreas to release insulin.

   - Helps the body to use insulin more effectively.

### Indications:

- Used to treat type 2 diabetes mellitus in adults.

- Helps in reducing the risk of diabetes-related complications when combined with a proper diet and exercise program.

### Dosage:

- The dosage of this combination is typically determined by the physician based on the patient's condition and response to treatment.

### Mechanism of Action:

This combination works by two mechanisms:

1. **Metformin** reduces glucose absorption in the intestines and hepatic glucose production.

2. **Glimepiride** enhances insulin secretion from the pancreatic beta cells and improves the body’s response to insulin.

### Key Benefits:

- Provides effective control over high blood sugar levels.

- Reduces the risk of complications such as heart disease, kidney damage, and nerve problems caused by uncontrolled diabetes.

### Side Effects:

- Common side effects include gastrointestinal discomfort (nausea, diarrhea), hypoglycemia (low blood sugar), dizziness, or weight gain.

### Precautions:

- Should not be used in patients with type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver dysfunction.

- Regular monitoring of blood glucose levels is advised.

- Not recommended during pregnancy or breastfeeding without medical advice.

Always take this medication as prescribed by your healthcare provider and ensure regular follow-up to manage blood sugar effectively.