Mitomycin C 10mg Mitomycin Injection, Color : Transparent

Mitomycin 10 mg injection is a chemotherapy medication used to treat various types of cancer. Here is a description of the medication:

• Active Ingredient: Mitomycin

   

   

• Drug Class: Antineoplastic agent (specifically, an antitumor antibiotic and alkylating agent).It works by interfering with the genetic material (DNA) of cancer cells, which stops their growth and multiplication, ultimately leading to their destruction.

   
   

   

• Formulation: It is typically a powder that is mixed with a liquid to be administered as an injection or infusion.

   

   

• Administration: It is administered by a healthcare professional in a hospital or clinic setting.It can be given intravenously (into a vein) or, for bladder cancer, as an intravesical instillation (infused directly into the bladder).It should not be self-administered.

   
   

   

Mitomycin 10 mg is used to treat a variety of cancers, including:

• Stomach cancer

   

   

• Pancreatic cancer

   

   

• Breast cancer

   

   

• Non-small cell lung cancer

   

   

• Cervical cancer

   

   

• Rectal cancer

   

   

• Anal cancer (off-label use)

   

   

• Bladder cancer (to prevent recurrence after surgery)

   

   

It may be used alone or in combination with other chemotherapy drugs as part of a treatment plan.

Mitomycin is a potent and highly toxic drug with a low therapeutic index.Its use requires careful monitoring due to potential side effects.

• Myelosuppression: A common and serious side effect is bone marrow suppression, which can lead to a significant decrease in blood cells:

   

   

  • Anemia: Low red blood cell count, causing fatigue and shortness of breath.

     

     

  • Leukopenia: Low white blood cell count, increasing the risk of serious infections.

     

     

  • Thrombocytopenia: Low platelet count, leading to an increased risk of bleeding and bruising.

     

     

  • Regular blood tests are essential to monitor these levels.

     

     

• Other Common Side Effects:

  • Nausea and vomiting

  • Loss of appetite

  • Fatigue

  • Hair loss (alopecia)

  • Sores in the mouth and throat (stomatitis)

     

     

  • Inflammation and irritation at the injection site

     

     

• Serious Side Effects:

  • Hemolytic Uremic Syndrome (HUS): A rare but potentially fatal condition involving anemia, low platelets, and irreversible kidney failure.

     

     

  • Pulmonary Toxicity: Can cause lung problems like a persistent cough, shortness of breath, and interstitial lung disease.

     

     

  • Kidney and Liver Damage: Mitomycin can affect kidney and liver function, requiring close monitoring.

     

     

• Contraindications: Mitomycin is not recommended for patients with:

  • A known allergy to the drug.

  • Existing blood disorders like pancytopenia, leukopenia, or thrombocytopenia.

  • Acute infections.

  • A perforation in the bladder wall (for intravesical use).

     

     

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