Mupirocin

Mupirocin is a topically used antibiotic from a strain of pseudomonas fluorescens. It has shown excellent activity against gram-positive staphylococci and streptococci. The antibiotic is used primarily for the treatment of primary and secondary skin disorders, nasal infections, and wound healing. Mupirocin is a rna synthetase inhibitor antibacterial. The mechanism of action of mupirocin is as a rna synthetase inhibitor.
Mupirocin is a natural crotonic acid derivative extracted from pseudomonas fluorescens. Mupirocin inhibits bacterial protein synthesis by specific reversible binding to bacterial isoleucyl trna synthase.