Naproxen

Naproxen is an anti-inflammatory agent with analgesic & antipyretic properties. Both the acid & its sodium salt are used in the treatment of rheumatoid arthritis & other rheumatic or musculoskeletal disorders, dysmenorrhea & acute gout. Naproxen is a nonsteroidal antiinflam- matory drug. The mechanism of action of naproxen is as a cyclooxy- genase inhibitor. The chemical classification of naproxen is nonsteroidal anti-inflammatory compounds.
Naproxen is a propionic acid derivative and a non-steroidal antiinflam- matory drug with anti-inflammatory, antipyretic & analgesic activities. Naproxen inhibits the activity of the enzymes cyclo-oxygenase I and ii, resulting in a decreased formation of precursors of prosta- glandins & thromboxanes. The resulting decrease in prostaglandin synthesis is responsible for the therapeutic effects of naproxen. naproxen also causes a decrease in the formation of thromboxane a2 synthesis, by thromboxane synthase, thereby inhibiting platelet aggregation.